Results 301 to 310 of about 305,172 (361)

Myelin Lipid Composition in the Central Nervous System Is Regionally Distinct and Requires Mechanistic Target of Rapamycin Signaling

Glia, EarlyView.
Brain oligodendrocytes have lower rates of cholesterol synthesis and higher rates of lipoprotein uptake than spinal cord oligodendrocytes. Myelin lipid content is higher in CNS regions with larger average axon diameter. Brain and spinal cord myelin cholesterol content is innately different, while myelin fatty acid content can be modulated by fiber ...
Marie L. Mather, Angelina V. Evangelou, Jennifer N. Bourne, Wendy B. Macklin, Teresa L. Wood   +4 more
wiley   +1 more source

AIDS-Associated <i>Talaromyces marneffei</i> Infection with Thoracic Spinal Cord Involvement Leading to Paraplegia: A Case Report and Literature Review. [PDF]

Infect Drug Resist
Guo Y, Song Y, Peng X, Zhou X, Zhou H, Xu L, Zhu B.   +6 more
europepmc   +1 more source

What Does Iron Mean to an Oligodendrocyte?

Glia, EarlyView.
ABSTRACT Iron is essential for life and plays a key role in multiple fundamental cellular functions. The brain has the highest rate of energy consumption, and within the brain, oligodendrocytes have the highest level of oxidative metabolism per volume. Oligodendrocytes also stain the strongest for iron.
Quinn W. Wade, James R. Connor
wiley   +1 more source

Faecal occult blood testing in persons aged 50-74 years with established spinal cord injury: a prospective case series. [PDF]

Spinal Cord Ser Cases
Wu MY, Tung C, Clark-Dickson M, Arthurs S, Nario S, Norton ID.   +5 more
europepmc   +1 more source

Cardiovascular disease risk and the need for prevention after paraplegia determined by conventional multifactorial risk models: The Stockholm spinal cord injury study

, 2011
Kerstin Wahman, Mark S. Nash, JE Lewis, Åke Seiger, Richard Levi   +4 more
openalex   +1 more source

Pathways to Progressive Disability in Multiple Sclerosis: The Role of Glial Cells in Chronic CNS Inflammation

Glia, EarlyView.
ABSTRACT Multiple sclerosis (MS) is the most common non‐infectious inflammatory CNS disease, characterized by progressive neurodegeneration and focal demyelinated lesions. Traditionally considered an autoimmune disease, MS is driven by the immune system's attack on CNS myelin, resulting in cumulative disability.
Volker Siffrin
wiley   +1 more source

The p.R321C mutation in the p62 protein is associated with abnormalities in the central nervous system. [PDF]

Sci Rep
Usategui-Martín R, Esteban-López V, Chantre-Fortes E, Sánchez-Martín M, Riancho JA, López DE, González-Sarmiento R.   +6 more
europepmc   +1 more source

Mapping Glial Autophagy Dynamics in an Amyotrophic Lateral Sclerosis Mouse Model Reveals Microglia and Astrocyte Autophagy Dysfunction

Glia, EarlyView.
In SOD1 mice, symptomatic spinal microglia and astrocytes show increased autophagy flux with greater dysfunction and SOD1 inclusions in astrocytes. Dysfunction was transient (end stage glia displayed control comparable levels of autophagy parameters). ABSTRACT Amyotrophic lateral sclerosis (ALS) is defined by motor neuron death.
Nirma D. Perera, Subhavi De Silva, Doris Tomas, Brittany Cuic, Bradley J. Turner   +4 more
wiley   +1 more source

Cordycepin ameliorates morphine tolerance by inhibiting spinal cord ferroptosis and inflammation via targeting SIRT1. [PDF]

Int J Med Sci
Li Z, Liu J, Ju J, Peng X, Zhao W, Ren J, Jia X, Wang J, Gao F.   +8 more
europepmc   +1 more source

Ultra‐Hypofractionated Radiotherapy for Early‐Stage Glottic Cancer: Real‐World Data From a Single Center

Head &Neck, EarlyView.
ABSTRACT Background In recent years, smaller‐volume radiotherapy has attracted attention. It appears to be a safe and effective treatment for glottic laryngeal cancer. This study evaluated the results of ultra‐hypofractionated radiotherapy for early glottic laryngeal cancer in unfit patients.
Mete Gundog, Esin Kiraz
wiley   +1 more source