Results 111 to 120 of about 125,751 (335)
PLoS Biology, 2010 Unlike those in the periphery, nerve fibers in the central nervous system (brain and spinal cord) do not recover from traumatic injury. This makes disabilities from spinal cord damage permanent, with the severity depending on the location of the cord injury.
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The Locus Coeruleus‐Periaqueductal Gray GABAergic Projection Regulates Comorbid Pain and Depression
Advanced Science, EarlyView.LC‐GABA neurons exhibit elevated activity to noxious and aversive stimuli in chronic pain, and their activation alleviates pain‐ and depression‐like behaviors. While LC‐GABA neurons target LC‐NA neurons and GABA and Glu neurons in the vlPAG, they modulate the pain responses of LC‐NA neurons but regulate pain‐ and depression‐like behaviors through their
Yuan Gao +7 more
wiley +1 more source
Mechanism of Electricacupuncture Treating Detrusor Bladder Neck Dyscoordination After Suprasacral Spinal Cord Injury by Proteomics [PDF]
arXivObjectives This study aimed to elucidate the potential mechanisms of electroacupuncture (EA) in restoring detrusor-bladder neck dyssynergesia (DBND) following suprasacral spinal cord injury. Methods A total of 52 adult female Sprague-Dawley rats were randomly assigned to either a sham group (n=12) or a spinal cord injury model group (n=40).
arxiv
OPERATION IN SPINAL-CORD INJURIES
Annals of Surgery, 1904 n ...
Mixter, Samuel J., Chase, Henry Melville
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Advanced Science, EarlyView.This study develops a cartilage‐targeted DNA origami system (OCS) that protects and delivers si‐Stat3 to chondrocytes. OCS reduces MMP13 expression, enhances extracellular matrix stability, and lowers oxidative stress while improving cell survival. In vivo, OCS decreases cartilage degradation biomarkers and promotes tissue repair factors, demonstrating
Qi Lv +8 more
wiley +1 more source
Toward Deep Learning-based Segmentation and Quantitative Analysis of Cervical Spinal Cord Magnetic Resonance Images [PDF]
arXivThis research proposal discusses two challenges in the field of medical image analysis: the multi-parametric investigation on microstructural and macrostructural characteristics of the cervical spinal cord and deep learning-based medical image segmentation.
arxiv
Epidemiology of spinal cord injury
Experimental Neurology, 1975 Accidents are the cause of some 50 deaths per 100 000 population each year in the US; some 3% of these are from traumatic spinal cord injury alone. Traumatic spinal cord injury in socioeconomically advanced countries, has a probably annual incidence rate of 3 per 100 000 population.
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Delayed Transplantation of Neural Stem Cells Improves Initial Graft Survival after Stroke
Advanced Science, EarlyView.Delayed transplantation of human iPSC‐derived neural progenitor cells (NPCs) enhances graft survival, proliferation, and axonal sprouting after stroke. Using bioluminescence imaging and histology in a mouse model of stroke, it is shown that NPC delivery at 7 days post‐stroke is more effective than acute transplantation, highlighting the importance of ...
Rebecca Z Weber +6 more
wiley +1 more source
Présentation d'une méthodologie d'évaluation de la faisabilité de la substitution sensorielle par électrostimulation linguale pour la prévention des escarres chez le bléssé médullaire paraplégique [PDF]
L'Escarre 31 (2006) 21-23, 2006 Pressure ulcers are recognized as a major health issue in individuals with spinal cord injuries and new approaches to prevent this pathology are necessary. An innovative health strategy is being developed through the use of computer and sensory substitution via the tongue in order to compensate for the sensory loss in the buttock area for individuals ...
arxiv