Results 141 to 150 of about 193,351 (379)

Trends in Damage Awards for Spinal Injuries [PDF]

open access: yes, 1968
This survey covers the years of 1965, 1966 and 1967. Cases have been grouped into injuries to vertebrae, injuries to intervertebral discs, aggravation of pre-existing injuries, and other spinal injuries, and then subdivided by year.
Solganik, Vivian
core   +1 more source

Lipid Droplets Metabolism Mediated by ANXA7‐PPARγ Signaling Axis Regulates Spinal Cord Injury Repair in Mice

open access: yesAdvanced Science, EarlyView.
This work proposes a new mechanism for the regulation of LDs metabolism by ANXA7/PPARγ. ANXA7 can interact with PPARγ to promote its stability. ANXA7 activation promotes PPARγ nuclear translocation, thus promoting LDs formation and interaction with mitochondria by promoting PLIN5 expression.
Lu Chen   +6 more
wiley   +1 more source

TRAUMATISMO RAQUIMEDULAR (TRM). REVISIÓN BIBLIOGRÁFICA

open access: yesRevista Médica Clínica Las Condes, 2020
Resumen: La complejidad del traumatismo raquimedular (TRM) y su impacto en la vida futura de los pacientes hace necesario actualizar constantemente los protocolos de su manejo. La fisiopatología del TRM hace que la atención prehospitalaria y hospitalaria
Gonzalo Arriagada, Nicolás Macchiavello
doaj  

Grasp Force Assistance via Throttle-based Wrist Angle Control on a Robotic Hand Orthosis for C6-C7 Spinal Cord Injury [PDF]

open access: yesarXiv
Individuals with hand paralysis resulting from C6-C7 spinal cord injuries frequently rely on tenodesis for grasping. However, tenodesis generates limited grasping force and demands constant exertion to maintain a grasp, leading to fatigue and sometimes pain.
arxiv  

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang   +9 more
wiley   +1 more source

Microenvironmental Modulation for Therapeutic Efficacy of Extracellular Vesicles

open access: yesAdvanced Science, EarlyView.
Recent studies highlighted the heterogeneity of EVs and the influence of microenvironmental signals on their therapeutic efficacy. This review offers a comprehensive overview of strategies and mechanisms to optimize the therapeutic efficacy of EVs through physical, biochemical, and mechanical modulation.
Bilu Xiang   +4 more
wiley   +1 more source

Circadian modulation of microglial physiological processes and immune responses

open access: yesGlia, Volume 71, Issue 2, Page 155-167, February 2023., 2023
Main Points Microglia are rhythmic cells with an oscillatory expression in clock genes, cytokines, and other microglial markers. Microglial circadian rhythms determine their physiological function and immune responses. Abstract Microglia is considered the central nervous system (CNS) resident macrophages that establish an innate immune response against
Mara A. Guzmán‐Ruiz   +11 more
wiley   +1 more source

Convolutional Deep Operator Networks for Learning Nonlinear Focused Ultrasound Wave Propagation in Heterogeneous Spinal Cord Anatomy [PDF]

open access: yesarXiv
Focused ultrasound (FUS) therapy is a promising tool for optimally targeted treatment of spinal cord injuries (SCI), offering submillimeter precision to enhance blood flow at injury sites while minimizing impact on surrounding tissues. However, its efficacy is highly sensitive to the placement of the ultrasound source, as the spinal cord's complex ...
arxiv  

Exoskeleton Knee Compliance Improves Gait Velocity and Stability in a Spinal Cord Injured User: A Case Report [PDF]

open access: yesarXiv, 2019
Spinal cord injuries frequently impair the ability to walk. Powered lower limb exoskeletons offer a promising solution to restore walking ability. However, they are currently restricted to even ground. We hypothesized that compliant exoskeleton knees could decrease required effort to maneuver on uneven terrain, and increase gait velocity and stability.
arxiv  

Home - About - Disclaimer - Privacy