Results 201 to 210 of about 125,751 (335)

Calpastatin, a calpain specific inhibitor, reduce seizures in a mouse model of temporal lobe epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Epilepsy is a chronic condition characterized by unpredictable and recurrent spontaneous seizures. In a previous study, we reported that pharmacological inhibition of calpain prevented epileptogenesis in the rat pilocarpine model. In this study, we demonstrate that transgenic overexpression of calpastatin, the endogenous inhibitor of calpain ...
Philip M. Lam   +3 more
wiley   +1 more source

Return to work after traumatic spinal fractures and spinal cord injuries: a retrospective cohort study. [PDF]

open access: yesSci Rep, 2023
Keihanian F   +6 more
europepmc   +1 more source

Exploring the Neuroprotective Role of Selenium: Implications and Perspectives for Central Nervous System Disorders

open access: yesExploration, EarlyView.
Selenium (Se) is a crucial element in selenoproteins, key biomolecules for physiological function in vivo. Central nervous system can express all 25 kinds of selenoproteins, which protect neurons by reducing oxidative stress and inflammatory response. Neuroprotection is being investigated through the biological study of Se.
Guanning Huang   +4 more
wiley   +1 more source

Novel carbon dots with dual Modulatory effects on the bone marrow and spleen as a potential therapeutic candidate for treating spinal cord injury

open access: yesBioactive Materials
Spinal cord injury triggers leukocyte mobilization from the peripheral circulation to the injury site, exacerbating spinal cord damage. Simultaneously, bone marrow hematopoietic stem cells (HSCs) and splenic leukocytes rapidly mobilize to replenish the ...
Junjin Li   +19 more
doaj  

Cervical vertebral and spinal cord injuries in rollover occupants. [PDF]

open access: yesInj Epidemiol
Al-Salehi L   +5 more
europepmc   +1 more source

Missed injuries of the spinal cord. [PDF]

open access: bronze, 1982
G Ravichandran, J R Silver
openalex   +1 more source

Structurally and Functionally Adaptive Biomimetic Periosteum: Materials, Fabrication, and Construction Strategies

open access: yesExploration, EarlyView.
Schematic illustration of structural and functional biomimicry. The upper part shows BP with various structures such as monolayered, surface‐microstructural, bilayered and multilayered. The bottom part exhibits BP with different functions including immune regulation, drugs/cells/factors/ions loading, as well as bioelectrical stimulation and ...
Yuhan Du   +7 more
wiley   +1 more source

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