Results 131 to 140 of about 723,074 (354)

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

3D MRI Tract‐Specific Spinal Cord Lesion Pattern Improves Prediction of Distinct Neurological Recovery

Annals of Clinical and Translational Neurology
Objective To distinguish lateralized motor‐ and sensory‐tract damage after acute spinal cord injury (SCI) and explore its predictive power for motor and sensory recovery. Methods Thirty‐five SCI patients (two female) from a multi‐center data set (placebo‐
Lynn Farner, Tim M. Emmenegger, Simon Schading‐Sassenhausen, Julia Berroth, Maryam Seif, Armin Curt, Patrick Freund, The Nogo Inhibition in Spinal Cord Injury Study Group   +7 more
doaj   +1 more source

Different expression of macrophages and microglia in rat spinal cord contusion injury model at morphological and regional levels. [PDF]

, 2005
Macrophages and microglia are implicated in spinal cord injury, but their precise role is not clear. In the present study, activation of these cells was examined in a spinal cord injury model using 2 different antibodies against ED1 clone and ionized ...
Igawa, Hiroharu, Itano, Toshifumi, Janjua, Najima A., Miyamoto, Osamu, Norimatsu, Hiromichi, Okada, Maiko, Shibuya, Sei, Wu, Di   +7 more
core   +1 more source

Transcutaneous Spinal Cord Stimulation and Motor Rehabilitation in Spinal Cord Injury: A Systematic Review

Neurorehabilitation and Neural Repair, 2019
Background. Epidural spinal electrical stimulation at the lumbar spinal level evokes rhythmic muscle activation of lower-limb antagonists, attributed to the central pattern generator.
Álvaro Megía García, D. Serrano-Muñoz, Julian Taylor, J. Avendaño-Coy, J. Gómez-Soriano   +4 more
semanticscholar   +1 more source

Vision‐Augmented Wearable Interfaces: Bioinspired Approaches for Realistic AI‐Human‐Machine Interaction

Advanced Materials Technologies, EarlyView.
This review presents recent progress in vision‐augmented wearable interfaces that combine artificial vision, soft wearable sensors, and exoskeletal robots. Inspired by biological visual systems, these technologies enable multimodal perception and intelligent human–machine interaction.
Jihun Lee, Gwuidong Ryu, Kisoo Kim, Feng Xu, Won Gu Lee   +4 more
wiley   +1 more source

Crosstalk between stem cell and spinal cord injury: pathophysiology and treatment strategies

Stem cell research & therapeutics, 2019
The injured spinal cord is difficult to repair and regenerate. Traditional treatments are not effective. Stem cells are a type of cells that have the potential to differentiate into various cells, including neurons.
Anwen Shao, Sheng Tu, Jianan Lu, Jianmin Zhang   +3 more
semanticscholar   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Height prediction of individuals with osteogenesis imperfecta by machine learning

Orphanet Journal of Rare Diseases
Background Osteogenesis imperfecta (OI) is a genetic disorder characterized by low bone mass, bone fragility and short stature. There is a significant gap in knowledge regarding the growth patterns across different types of OI, and the prediction of ...
Hongjiang Yang, Wenbiao Zhu, Bo Li, Hao Wang, Cong Xing, Yang Xiong, Xiuzhi Ren, Guangzhi Ning   +7 more
doaj   +1 more source

Quantification of Lower Limb Kinematics During Swimming in Individuals with Spinal Cord Injury

Sensors
Spinal cord injuries (SCI) often result in impaired motor functions. To quantify these impairments, swimming patterns were analyzed in individuals with SCI.
Melina Giagiozis, Sabrina Imhof, Sibylle Achermann, Catherine R. Jutzeler, László Demkó, Björn Zörner   +5 more
doaj   +1 more source

MRI in traumatic spinal cord injury: from clinical assessment to neuroimaging biomarkers.

Lancet Neurology, 2019
Traumatic spinal cord injury occurs when an external physical impact damages the spinal cord and leads to permanent neurological dysfunction and disability, and it is associated with a high socioeconomic burden.
P. Freund, Maryam Seif, N. Weiskopf, Karl J. Friston, A. Curt   +4 more
semanticscholar   +1 more source