Results 191 to 200 of about 723,074 (354)

Metabolic and biochemical profiling reveals phenotypic heterogeneity in Zucker diabetic fatty rats

Animal Models and Experimental Medicine, EarlyView.
Genetically uniform Zucker Diabetic Fatty (ZDF) rats spontaneously develop four distinct metabolic phenotypes despite identical housing and diet conditions. Each phenotype exhibits unique biomarker signatures encompassing glucose homeostasis, insulin secretion, polyol pathway activation, oxidative stress, inflammatory cytokines, and neurotrophic ...
Marek Lepáček, Pavol Boďo, Barbora Kaločayová, Marta Šoltésová Prnová   +3 more
wiley   +1 more source

Cuproptosis in spinal cord injury: emerging mechanisms and immunological relevance. [PDF]

Ann Med
Li LH, Zhang JQ, Ying XH, Huang Y, Xu CC, Wang XX, He KL, Ma RJ.   +7 more
europepmc   +1 more source

Comparative virology and pathology of Monkeypox virus in Syrian hamsters, C57BL/6, and BALB/c mice: A framework for preclinical model selection

Animal Models and Experimental Medicine, EarlyView.
This study compared monkeypox virus (MPXV) infection in three small animal models: Syrian hamsters, C57BL/6 mice, and BALB/c mice. Following intraperitoneal inoculation, Syrian hamsters exhibited the highest susceptibility, with rapid systemic viral dissemination, elevated splenic and renal viral burdens, and severe histopathological damage, followed ...
Xiaohui Wei, Jing Wu, Hekai Yang, Na Li, Binbin Zhao, Wanjun Peng, Na Rong, Wei Zhang, Jing Xue, Jiangning Liu   +9 more
wiley   +1 more source

Traumatic Spinal Cord Injury—Repair and Regeneration

Neurosurgery, 2017
Christopher S Ahuja, Satoshi Nori, Lindsay A. Tetreault, Jefferson R. Wilson, B. Kwon, J. Harrop, D. Choi, M. Fehlings   +7 more
semanticscholar   +1 more source

Spinal Cord Injury

Journal of Pediatric Rehabilitation Medicine, 2012
openaire   +3 more sources

Establishment and multifaceted characterization of a graded spinal cord injury model based on graduated impact depth

Animal Models and Experimental Medicine, EarlyView.
We established a graded spinal cord injury (SCI) model based on graduated impact depth, which was subsequently characterized across multiple dimensions, including locomotor function, imaging, histology, and transcriptomic profiles. We further identified transcriptomic changes in graded SCI at different time points postinjury and investigated the ...
Gang Zhou, Yue Hu, Zhimin Li, Shiyuan Han, Yuejia Li, Yongning Li, Jun Gao   +6 more
wiley   +1 more source

Regional Molecular Diversity in Chronic Spinal Cord Injury. [PDF]

Cell Mol Neurobiol
Choi CI, Kim HN, Yoon H, Radulovic M, Simon WL, Scarisbrick IA.   +5 more
europepmc   +1 more source

Research progress on biomarkers of traumatic brain injury

Animal Models and Experimental Medicine, EarlyView.
Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen, Si Cheng, Shuyi Chen, Mengyue Wang, Tangying Li, Weicheng Xu, Yifan Zhang, Ping Yuan, Lei Shi   +8 more
wiley   +1 more source

Towards an understanding of disturbed sleep phenotypes after traumatic spinal cord injury. [PDF]

J Rehabil Med
Graves-Dixon LY, May A, Redline S, Xu Z, Sun J, Ferguson AR, Bogie KM.   +6 more
europepmc   +1 more source

The 2019 revision of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)—What’s new?

Spinal Cord, 2019
R. F. S. P. W. D. E. J. L. S. A. M. J. M. G. M. Rüdig Betz Biering-Sørensen Burns Donovan Graves Guest J, R. Betz, F. Biering-Sørensen, S. Burns, W. Donovan, D. Graves, J. Guest, L. Jones, S. Kirshblum, A. Krassioukov, M. Mulcahey, M. Schmidt Read, G. Rodriguez, R. Rupp, C. Schuld, K. Tansey, K. Walden   +16 more
semanticscholar   +1 more source