Results 161 to 170 of about 46,554 (341)

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Comparison of the SMI Technique and CEUS for the Assessment of Microvasculature in Leiomyosarcoma and Its Clinical Value for Application

Journal of Clinical Ultrasound, EarlyView.
SMI and CEUS can clearly reflect the microvascular situation in fibroids and effectively guide the clinical treatment of patients with uterine fibroids, but the effect of SMI is better than that of CEUS in guiding the treatment of patients, which can provide a reference for the selection of clinical treatment programs.
Qiufeng Li, Junbin Du
wiley   +1 more source

Family Game Show-style Didactic for Teaching Nervous System Disorders during Emergency Medicine Training [PDF]

, 2020
Boysen Osborn, Megan, Brinley Rajagopal, Alaina, Sudario, Gabriel, Weiland, David   +3 more
core  

Acupuncture alters cortical and corticomuscular functional connectivity in stroke patients with motor dysfunction

Journal of Intelligent Medicine, EarlyView.
Abstract Stroke is a leading cause of global mortality and disability, often resulting in severe motor dysfunction. Acupuncture has shown promise in stroke rehabilitation, but its neural mechanisms remain unclear. This study investigated the immediate effects of acupuncture at GV26, PC6, and SP6 on cortical and corticomuscular functional connectivity ...
Rui Xu, Siheng Chen, Zhongxiang Zhang, Jin Yang   +3 more
wiley   +1 more source

Intramedullary meningioma of spinal cord: Case report of a rare tumor highlighting the differential diagnosis of spinal intramedullary neoplasms

, 2014
Ishita Pant, Sujata Chaturvedi, VinodKumar Singh Gautam, Rima Kumari   +3 more
openalex   +1 more source

Towards Clinical Translation of Intravoxel Incoherent Motion MRI: Acquisition and Analysis Consensus Recommendations

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Intravoxel incoherent motion (IVIM) MRI allows for simultaneous assessment of tissue microcirculation (perfusion) and diffusion of water. In single‐center studies, IVIM has shown great potential for diagnosis, treatment outcome prediction, and treatment monitoring for many different diseases and organs.
Eric E. Sigmund, Susanne S. Rauh, Mami Iima, Christian Federau, Diego Hernando, Oscar Jalnefjord, Jacobus F. A. Jansen, Jonas Jasse, Neil Peter Jerome, Misha P. T. Kaandorp, Sila Kurugol, Frederik B. Laun, Mira M. Liu, Alexandra Ljimani, Thoralf Niendorf, David A. Reiter, Mohammed Salman Shazeeb, Amita Shukla‐Dave, Julia Stabinska, Andreas Wetscherek, Peter T. While, Dan Wu, Denis Le Bihan, Oliver J. Gurney‐Champion   +23 more
wiley   +1 more source

A single-center cost analysis of treating primary and metastatic brain cancers with either brain laser interstitial thermal therapy (LITT) or craniotomy [PDF]

, 2016
Kim, Albert H, Leuthardt, Eric C, Sylvester, Pete, Voigt, Jeff   +3 more
core   +2 more sources

Barriers to nutrition following neurosurgery: A descriptive cohort study

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Neurological trauma results in a state of hypermetabolism. Existing literature has explored barriers to adequate nutrition following traumatic brain injury. Despite clinical similarities, it remains unclear whether similar nutritional barriers are faced following both planned and emergency neurosurgical procedures.
Dale Palmer, Melissa Zhou, Suzie Ferrie
wiley   +1 more source

The Clinical Efficacy of High‐Voltage Long‐Duration Pulsed Radiofrequency Treatment in Pudendal Neuralgia: A Retrospective Study

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Background Patients with pudendal neuralgia (PN) experience long‐lasting chronic pain, hyperalgesia, and comorbid emotional disorders, such as depression and anxiety. Treatment via conventional pulsed radiofrequency (PRF) current carries a significantly high rate of failure.
Cheng‐Long Wang, Tao Song
wiley   +1 more source

USP7 Regulates TRPV1 Deubiquitination to Mediate Chondrocyte Ferroptosis and Alleviate Osteoarthritis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease characterized by chondrocyte dysfunction. In this study, we explored the function and mechanism of ubiquitin‐specific protease 7 (USP7) in chondrocyte ferroptosis in OA. The USP7, TRPV1, collagen II, and GPX4 levels in knee joint tissue were detected using immunohistochemistry ...
Jun Li, Ding Chen, Wei‐Ye Zhong
wiley   +1 more source