Results 121 to 130 of about 114,217 (301)

Facile Single‐Nanocomposite 4D Bioprinting of Dynamic Hydrogel Constructs with Thickness‐Controlled Gradient

open access: yesAdvanced Science, EarlyView.
This study presents a novel and facile thickness‐modulated 4D bioprinting approach using a smart bioink made of gelatin, GelMA, and MXene. Leveraging computational models, it creates living constructs with programmable unidirectional and bidirectional curvatures under a single UV exposure.
Jiahui Lai   +7 more
wiley   +1 more source

An Effective Oral Drug Delivery Route for Pharmacokinetic Complications: Spirulina Lipid Nanotechnology System

open access: yesAdvanced Science, EarlyView.
Spirulina‐nano system facilitates the formation of drug coating on spirulina's surface through electrostatic adsorption. It targets intestinal villi effectively and overcomes the pharmacokinetic complications of IBS‐D. This system successfully carried out the treatment of multiple symptoms, including diarrhea, visceral hypersensitivity, mental symptoms,
Jiahui Ye   +7 more
wiley   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

open access: yesAdvanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao   +4 more
wiley   +1 more source

A Programmable, 3D Neuron‐On‐Chip Platform Integrating Near Real‐Time Biosensing and Multiaxial Loading for Mechanobiological Injury Profiling

open access: yesAdvanced Science, EarlyView.
A programmable 3D Neuron‐Injury‐on‐a‐Chip platform integrates multiaxial mechanical loading with ultrasensitive electrochemical biosensing to decode neuronal responses in real time. By mimicking physiologically relevant extension–torsion forces, the system reveals load‐specific biomarker trajectories (T‐Tau, NFL), gene regulation, and apoptosis.
Sultan Khetani   +12 more
wiley   +1 more source

Spinal cord stimulation for neuropathic pain: current perspectives

open access: yesJournal of Pain Research, 2014
Tilman Wolter Interdisciplinary Pain Centre, University Hospital Freiburg, Freiburg, Germany Abstract: Neuropathic pain constitutes a significant portion of chronic pain.
Wolter T
doaj  

Open Challenges and Opportunities in Piezoelectricity for Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
This review provides an intriguing review of the recent advancements, challenges, and future perspectives regarding the application of piezoelectric scaffolds in tissue regeneration. The detailed exposition is anticipated to propel the advancement of personalized and intelligent piezoelectric implants, thereby fostering significant progress in this ...
Xiaoling Deng   +7 more
wiley   +1 more source

Partial Reprogramming in Senescent Schwann Cells Enhances Peripheral Nerve Regeneration via Restoration of Stress Granule Homeostasis

open access: yesAdvanced Science, EarlyView.
In this study, it is discovered that pathological accumulation of Runx2+ Schwann cell clusters​ during axonal regeneration is a key factor impairing nerve repair in aging. This pathology is associated with ​dysregulation of stress granule homeostasis.
Peilin Wang   +10 more
wiley   +1 more source

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