Role of SoxE transcription factors in development and disease
Developmental Dynamics, EarlyView.Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
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Functional Recovery Following Spinal Cord Stimulation in a Patient Utilizing Prospera Spinal Cord Stimulation System with Multiphase Stimulation. [PDF]
Orthop Rev (Pavia)Hasoon J, Urits I.
europepmc +1 more source
Novel planning pipeline utilizing the Surgical Theater system for pediatric epilepsy surgery
Epilepsia Open, EarlyView.Abstract Objective Advances in the analysis and collation of radiographic datasets have enhanced presurgical planning for various neurosurgical procedures, including clipping of cerebral aneurysms, surgical resection of tumors, and arteriovenous malformation management.
Lisa B. E. Shields +4 more
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Spinal cord stimulation as a novel neuromodulation strategy for enhancing language recovery in post-stroke aphasia: a hypothesis. [PDF]
Front Hum NeurosciLu D +5 more
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Antibody kinetics against tetanus toxoid before and after primary vaccination of foals
Equine Veterinary Journal, EarlyView.Abstract Background Vaccination recommendations for foals against Clostridium tetani vary. Available studies assessing foal immune responses, maternal antibody interference, or individual variation often used small foal numbers. Objectives To quantify antibody responses after tetanus vaccination in foals and explore associations with passively ...
Katharina Olbrich +2 more
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From Prediction to Monitoring: Toward a Translational Framework of Biomarkers in Spinal Cord Stimulation. [PDF]
BiomedicinesFabregat-Cid G +2 more
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Exploration, EarlyView.This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi +5 more
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Combined bidirectional spinal cord stimulation for refractory neuropathic pelvic pain: a case report. [PDF]
Front Pain Res (Lausanne)Perper Y, Taub A, Perper J.
europepmc +1 more source
Exploration, EarlyView.Osteoarthritis pain arises not only from joint damage but also from inflammation, abnormal bone changes, and excessive nerve activation inside the joint. In this study, we developed an injectable nanomedicine, LAC, that responds to the acidic environment of osteoarthritic joints to locally release two approved drugs, reducing inflammation, limiting ...
Junyan Liu +12 more
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Hydrogel‐Based Bioelectronics: From Therapy and Sensing to Neuromorphic Computation
FlexTech, EarlyView.This review establishes a material–conduction–property–application framework connecting hydrogel chemistry and charge transport with therapy, sensing, closed‐loop feedback, and neuromorphic computation. ABSTRACT Bioelectronics establish bidirectional communication between living systems and electronic devices, providing an enabling platform for ...
Jianlong Hong +7 more
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