Results 271 to 280 of about 228,570 (332)

Contemporary and Emerging Therapies in the Management of Refractory Angina: A Clinical Review

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Refractory angina (RA) represents a growing challenge in clinical cardiology, particularly in patients with obstructive coronary artery disease (CAD) who remain symptomatic despite optimal medical therapy and who are not candidates for revascularization.
Alex Angers‐Goulet, Siddhartha Mengi, David Garcia Labbé, Can Manh Nguyen, Jean‐Michel Paradis   +4 more
wiley   +1 more source

Comparative efficacy of short-term spinal cord stimulation and pulsed radiofrequency in zoster-associated pain: a stratified database study. [PDF]

Front Neurol
Lu F, Li J, Zhong J, Li X, Song L, Ye L, Xiao H.   +6 more
europepmc   +1 more source

Advances in Triboelectric Nanogenerators With Rotating Structure

Carbon Energy, EarlyView.
The rotating TENG has been widely studied for its superiorities of simple structure, high efficiency, and stable output. This review introduced the four different principles of rotating TENG and offered a thorough summary for performance and application research through three‐level classification. Importantly, the current existing problems, challenges,
Chuguo Zhang, Chunxu Xue, Yutong Chen, Yujie Qiang, Seeram Ramakrishna   +4 more
wiley   +1 more source

10 kHz spinal cord stimulation vs. traditional low-frequency spinal cord stimulation for the treatment of diabetes peripheral neuropathic pain: study protocol for a multi-center randomized controlled clinical trial. [PDF]

Front Neurol
Li C, Liu CH, Li YF, Hu HM, Shi Q, Liu AX, Liu WH, Zhang Y, Mao P, Fan BF.   +9 more
europepmc   +1 more source

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses and Dose Titration of Bexicaserin in Healthy Participants in a Randomized, Double‐Blind, Placebo‐Controlled Study

Clinical Pharmacology in Drug Development, EarlyView.
Abstract Bexicaserin (LP352) is a selective superagonist of the 5‐hydroxytryptamine 2C (5‐HT2C) receptor currently in development for the treatment of seizures that arise from developmental and epileptic encephalopathies. This phase 1, double‐blind, placebo‐controlled multiple ascending dose (MAD) study assessed the safety, tolerability, and ...
Jonathan Williams, Rosa Chan, Chad Orevillo, Gale O'Connell, Dewey McLin, Shikha Polega, Nuggehally R. Srinivas, Randall Kaye   +7 more
wiley   +1 more source

A scoping review of spinal cord stimulation for phantom limb pain. [PDF]

Interv Pain Med
Jaffee S, Verma R, Vaezi M, Kite T, Tomycz N.   +4 more
europepmc   +1 more source

The endocannabinoid system regulates both ependymoglial and neuronal cell responses to a tail amputation in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background The endocannabinoid system is a neuromodulatory system implicated in cellular processes during both development and regeneration. The Mexican axolotl, one of only a few vertebrates capable of central nervous system regeneration, was used to examine the role of the endocannabinoid system in the regeneration of the tail and spinal ...
Michael Tolentino, Sarah E. Walker, Gaynor E. Spencer, Robert Carlone   +3 more
wiley   +1 more source

Stimulation intensities influence the effects of spinal cord stimulation in disorders of consciousness: an fNIRS study. [PDF]

Neurophotonics
Liu A, Ge Q, Jiao L, Peng H, Sun Y, Han S, Zhang Q, Si J, He J.   +8 more
europepmc   +1 more source

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

Multi-system benefits of non-invasive spinal cord stimulation following cervical spinal cord injury: a case study. [PDF]

Bioelectron Med
Samejima S, Shackleton C, Malik RN, Hosseinzadeh A, Rempel L, Phan AD, Williams A, Nightingale T, Ghuman A, Elliott S, Walter M, Krogh K, Berger M, Lam T, Sachdeva R, Krassioukov AV.   +15 more
europepmc   +1 more source