Results 81 to 90 of about 1,190,854 (251)

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

open access: yesAdvanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan   +10 more
wiley   +1 more source

Effects of lithium on electrical activity and potassium ion distribution in the vertebrate central nervous system [PDF]

open access: yes, 1983
Three different regions of the vertebrate central nervous system maintained in vitro (frog spinal cord, guinea pig olfactory cortex and hippocampus) have been used to investigate how Li+ influences membrane potential, membrane resistance, action ...
H. Emmert   +7 more
core   +1 more source

Treating spinal cord injury with implanted spinal cord stimulators

open access: yes, 2022
Spinal cord injury (SCI), as a devastating spinal cord disorder, remains a critical problem affecting millions of people all over the world. Although the mortality of SCI has decreased owing to medical advancement, it still implicates sensory, motor, and
You, H   +5 more
core   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

open access: yesAdvanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu   +2 more
wiley   +1 more source

Brain potential evoked by spinal cord stimulation from D-Wave catheter at the end of resection of spinal cord tumors

open access: yes, 2012
Introduction IntraOperative NeuroMonitoring (IONM) in spinal cord tumour surgery relies mostly onto the assessment of the integrity of the motor pathways, with Transcranial Motor Evoked Potentials, with the possible adjunct of Somatosensory Evoked ...
F. Pessina   +5 more
core   +2 more sources

Rebuilding motor function of the spinal cord based on functional electrical stimulation

open access: yesNeural Regeneration Research, 2016
Rebuilding the damaged motor function caused by spinal cord injury is one of the most serious challenges in clinical neuroscience. The function of the neural pathway under the damaged sites can be rebuilt using functional electrical stimulation ...
Xiao-yan Shen   +3 more
doaj   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

open access: yesAdvanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong   +17 more
wiley   +1 more source

Unintentionally intentional: unintended effects of spinal stimulation as a platform for multi-modal neurorehabilitation after spinal cord injury

open access: yesBioelectronic Medicine
Electrical stimulation of spinal neurons has emerged as a valuable tool to enhance rehabilitation after spinal cord injury. In separate parameterizations, it has shown promise for improving voluntary movement, reducing symptoms of autonomic dysreflexia ...
Gerson N. Moreno Romero   +3 more
doaj   +1 more source

Spinal cord electrical stimulation for severe disturbance of consciousness after traumatic brain injury: A case report

open access: yesHeliyon
Background: Currently, the use of spinal cord electrical stimulations for patients with severe disorders of consciousness after traumatic brain injury remains limited, and long-term follow-up studies are even scarcer. To date, there have been few reports
Zhiwen Zhu, Xiaozhen Hu, Yajun Mao
doaj   +1 more source

Spinal cord injury /

open access: yes, 2012
Spinal Cord Injuries, the newest volume in the Handbook of Clinical Neurology series, offers a comprehensive and detailed overview of the rapidly evolving science and treatment of spinal cord injury.
Verhaagen, Joost., McDonald, John W.
core  

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