Results 131 to 140 of about 4,552 (301)
The association of rod curvature with postoperative outcomes in patients undergoing posterior lumbar interbody fusion for spinal stenosis [PDF]
Lin Han +6 more
openalex +1 more source
Depression, a prevalent neuropsychiatric disorder with unclear pathogenesis, involves dysfunctional adenylyl cyclase 8 (Adcy8) as a key risk factor. Chronic stress selectively reduces Adcy8 expression in the dorsal CA1 (dCA1) neurons. Depletion of Adcy8 in dCA1 excitatory neurons induces depressive‐like behaviors by impairing neuronal excitability and ...
Zi‐Jie Liu +14 more
wiley +1 more source
Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su +15 more
wiley +1 more source
Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age‐Associated Metabolic Abnormalities
This study identifies endothelial KDM5A as a key regulator of aging. KDM5A deficiency accelerates aging by enhancing H3K4me3‐mediated FABP4 expression, disrupting fatty acid metabolism, and promoting multi‐organ senescence. KDM5A restoration or FABP4 inhibition reverses these adverse effects and extends lifespan, positioning the KDM5A/FABP4 axis as a ...
Rifeng Gao +21 more
wiley +1 more source
A quasi‐periodic porous structure‐based temperature and pressure dual‐mode electronic skin was proposed. Benefiting from the quasi‐periodic porous structure, the temperature and pressure sensing performance of the electronic skin can be precisely constructed and optimized by changing the size of the porous structure. By analyzing the thermoelectric and
Xiaoguang Gao +5 more
wiley +1 more source
Automatic radiation-free evaluation of Cobb angle for spinal curvature based on fringe projection profilometry and deep learning technology [PDF]
Chi-Kuang Feng +5 more
openalex +1 more source
Abnormal Spinal Curvature as a Risk Factor for Pelvic Organ Prolapse [PDF]
Manizheh Sayyah-Melli, Mahasti Alizadeh
openalex +1 more source

