Results 221 to 230 of about 1,263,722 (262)

An essay on the general principles of the treatment of spinal curvatures

, 1905
Bigg, R. Heather 1853-1911
core  

Huntingtin Aggregate‐Responsive Autophagy Gene Circuit Mitigates Disease Pathology in R6/2 Mice

Advanced Science, EarlyView.
CD98‐mediated receptor‐mediated transcytosis enables LIP‐CD98 nanocarriers to cross the blood–brain barrier and deliver ARAA to neurons. mHTT aggregates activate the 11G–NarX sensor, initiating Auto‐P and Trans‐P signaling through the VP48–NarL relay.
Jie Zhu, Xi‐xiu Xie, Lei Li, Chen Tian, Hao‐tian Wang, Xiao‐jie Wang, Xiao‐lin Yu, Gui‐feng Zhang, Rui‐tian Liu   +8 more
wiley   +1 more source

<i>ScolioClass</i>: data-driven development of a new classification tool to evaluate adolescent idiopathic scoliosis optically diagnosed. [PDF]

Front Digit Health
Ćuković S, Neghina M, Petruse RE, Luković V, Stojić D, Zou Y.   +5 more
europepmc   +1 more source

Early‐Life Manganese Overexposure Activates Microglial Phagocytosis through the YY1/TREM2 Axis Leading to Hippocampal Synaptic Remodeling in Mice

Advanced Science, EarlyView.
Early‐life manganese exposure induces behavioral deficits and aberrant hippocampal synaptic remodeling by enhancing microglial phagocytosis in young adult male mice. Mechanistically, manganese promotes Yin Yang 1 (YY1)/triggering receptor expressed on myeloid cells 2 (TREM2) signaling through enhanced HIF1α‐mediated transcription and suppressed SMURF2 ...
Keyu Chen, Bin He, Kuan Liu, Zhuo Ma, Bin Xu   +4 more
wiley   +1 more source

A Modified Dot-Pattern Moiré Fringe Topography Technique for Efficient Human Body Surface Analysis. [PDF]

Sensors (Basel)
Wasim M, Ahsan ST, Ahmed L, Sagar S.
europepmc   +1 more source

Single‐Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age‐Associated Remodeling

Advanced Science, EarlyView.
Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li, Zhuoqiong Qiu, Xiaoyu Pan, Geyang Xu, Shanshan Peng, Ronghui Zhu, Qiuyang Luo, Xiaokai Fang, Xu Yao, Wei Li   +9 more
wiley   +1 more source

Barriers and facilitators of brace compliance in adolescents with spinal deformities: a qualitative study. [PDF]

BMC Musculoskelet Disord
Ghorbani F, Ranjbar H, Kamali M, Nemati Z, Razavi H, Babaee T.   +5 more
europepmc   +1 more source

H4K12 Lactylation Regulates NDUFS7 to Drive Microglia Reverse Electron Transport in Spinal Cord Injury

Advanced Science, EarlyView.
Lactate accumulation after SCI promotes H4K12la lactylation, which upregulates NDUFS7, triggering mitochondrial RET and ROS, enforcing pro‐inflammatory microglial polarization. MM@mPTC, a biomimetic nanotherapeutic, degrades LDHA in activated microglia, reducing H4K12la lactylation and blocking RET, thus curbing ROS, fostering a reparative phenotype ...
Chenglong Hong, Zhichen Jiang, Zhouwei Wu, Chenyu Wu, Jiang Liu, Kaijie Guo, Yihui Liang, Shaobo Xu, Yuchen Jin, Yong Xiao, Lei Guo, Hui Xu, Sunren Sheng, Chenggui Wang   +13 more
wiley   +1 more source

Prevalence of hypermobility in children and adolescents aged 10-13 years in correlation with postural defects-a preliminary report. [PDF]

Front Public Health
Czorniej KP, Kułak W.
europepmc   +1 more source

Effect of Minimally Invasive Pectus Correction on Thoracic Spinal Alignment in Pectus Excavatum and Carinatum Patients: A Retrospective Cohort Study. [PDF]

Interdiscip Cardiovasc Thorac Surg
Aydemir S, Mutlu F, Akin E, Karci E, Karacam V, Akcali O.   +5 more
europepmc   +1 more source