Results 141 to 150 of about 329,755 (256)

Concepts of Regeneration for Spinal Diseases in 2021. [PDF]

Int J Mol Sci, 2021
Yurube T, Han I, Sakai D.
europepmc   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

Cortical and spinal motor neurons controlling muscle behavior

, 2014
Motor neuron disease are neurological diseases characterized by progressive deterioration in motor neurons in brain, brain stem and spinal cord leading to muscle weakness and wasting.Approaches to motor diseases are he ...
Y. Torrente
core  

Comparison of Imaging Methods and Population Pattern in Dogs with Spinal Diseases in Three Periods between 2005 and 2022: A Retrospective Study. [PDF]

Vet Sci, 2023
Fuchs J, Domaniža M, Kuricová M, Lipták T, Ledecký V.   +4 more
europepmc   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Mechanisms involved in chronic neuropathic pain after avulsion injury

, 2010
PhDMotor vehicle accidents are the most common cause of injuries involving avulsion of spinal roots from the brachial or lumbosacral plexuses. This results in chronic intractable pain that is refractory to pharmacotherapy.
Chew, Daniel John
core  

Vertebral BMSC-EVs under estrogen deficiency drive senescence-related mitochondrial dysfunction in endplate chondrocytes via MRPL1 mRNA delivery

Experimental and Molecular Medicine
The growing population of postmenopausal women in an aging society has led to a heightened incidence of lumbar degenerative diseases (LDD). The degeneration of the vertebral endplate cartilage is considered the initial factor in LDD, but the effect of ...
Yiming Zhong, Zhuoxin Li, Haofeng Hong, Zhenda Zhao, Longting Chen, Zihuan Yang, Dongwei Fan, Wanqiong Yuan, Da Zou, Hua Tian, Chunli Song, Weishi Li, Huijie Leng   +12 more
doaj   +1 more source

Minimally Invasive Spinal Treatment (MIST)-A New Concept in the Treatment of Spinal Diseases: A Narrative Review. [PDF]

Medicina (Kaunas), 2022
Ishii K, Watanabe G, Tomita T, Nikaido T, Hikata T, Shinohara A, Nakano M, Saito T, Nakanishi K, Morimoto T, Isogai N, Funao H, Tanaka M, Kotani Y, Arizono T, Hoshino M, Sato K.   +16 more
europepmc   +1 more source

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

Advanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang, Qingqing Zhang, Xiuxiu Wang, Lixin Peng, Xinru Ji, Jiawei Wang, Yusi Zhang, Jiayang Huang, Junchao Yang, Shiqi Zhan, Yiping Xiao, Weilin Liu, Lidian Chen   +12 more
wiley   +1 more source

An Evolution Gaining Momentum-The Growing Role of Artificial Intelligence in the Diagnosis and Treatment of Spinal Diseases. [PDF]

Diagnostics (Basel), 2022
Wirries A, Geiger F, Oberkircher L, Jabari S.   +3 more
europepmc   +1 more source