Results 251 to 260 of about 483,667 (360)

Engineered Stem Cell Clusters for Extracellular Vesicles‐Mediated Gene Delivery to Rejuvenate Chondrocytes and Facilitate Chondrogenesis in Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
BMSCmotif+miR874/MS system is designed as a gene delivery platform utilizing engineered bone marrow mesenchymal stem cell (BMSC)‐derived extracellular vesicles (EVs) for intercellular communication to achieve sustained delivery of miRNA‐874‐3p. Rejuvenation of chondrocytes and promotion of chondrogenesis are achieved by inhibition of the NF‐κB pathway,
Yuezhou Wu   +7 more
wiley   +1 more source

Medical care for spinal diseases during the COVID-19 pandemic. [PDF]

open access: yesClinics (Sao Paulo), 2020
Silva RTE   +3 more
europepmc   +1 more source

In Vivo Cytosolic Delivery of Biomolecules into Neurons for Super‐Resolution Imaging and Genome Modification

open access: yesAdvanced Science, EarlyView.
The N1 peptide specifically targets neurons, enabling cytosolic delivery of fluorescent dyes and proteins for super‐resolution imaging and functional genetic modification. Abstract Efficient delivery of biomolecules into neurons has significant impacts on therapeutic applications in the central nervous system (CNS) and fundamental neuroscience research.
Xiaoqian Ge   +16 more
wiley   +1 more source

Phillygenin inhibits neuroinflammation and promotes functional recovery after spinal cord injury via TLR4 inhibition of the NF-κB signaling pathway

open access: yesJournal of Orthopaedic Translation
Background: Spinal cord injuries (SCIs) trigger a cascade of detrimental processes, encompassing neuroinflammation and oxidative stress (OS), ultimately leading to neuronal damage.
Yu Zhang   +6 more
doaj  

Visual Verticality Perception in Spinal Diseases: A Systematic Review and Meta-Analysis. [PDF]

open access: yesJ Clin Med, 2020
Obrero-Gaitán E   +5 more
europepmc   +1 more source

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