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Multiscale Cell–Cell Interactive Spatial Transcriptomics Analysis

open access: yesAdvanced Science, EarlyView.
In this study, we present the MultiScale Cell‐Cell Interactive Spatial Transcriptomics Analysis method, which unites the strengths of spatially resolved deep learning techniques with a topological representation of multi‐scale cell‐cell similarity relations.
Sean Cottrell, Guo‐Wei Wei
wiley   +1 more source

Estrogen Alleviates Sevoflurane‐Induced Neurotoxicity by Inhibiting ERα‐Tau Binding

open access: yesAdvanced Science, EarlyView.
Sevoflurane‐induced neurotoxicity exhibits sex differences, and estrogen can mitigate these effects; however, its protective action appears to be time‐window dependent, which may be related to the competitive binding of estrogen and Tau to ERα. Abstract Sevoflurane‐induced neurotoxicity is age‐dependent, but the role of sex differences is unclear ...
Feixiang Li   +8 more
wiley   +1 more source
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Nonsurgical Spinal Diseases

Spinal Neurosurgery, 2018
There are many disease processes which can have clinical manifestations similar to those produced by pathologies requiring surgical intervention. Demyelinating processes, such as multiple sclerosis, neurodegenerative disease such as amyotrophic lateral sclerosis, and infections such as HIV can all produce classic signs and symptoms of myelopathy.
Lahiru Ranasinghe, Aimee M. Aysenne
openaire   +2 more sources

Differential Diagnosis of Spinal Diseases

Veterinary Clinics of North America: Small Animal Practice, 2010
Preparation of a logical list of differential diagnoses is a key step in the diagnostic approach for dogs and cats with spinal disorders. This article presents the main differential diagnoses for patients with spinal diseases grouped according to lesion localization.
Ronaldo C. da Costa, Sarah A. Moore
openaire   +4 more sources

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