Results 241 to 250 of about 1,649,200 (352)
Accelerating Bone Healing With METTL3 Overexpressed Adipose‐Derived Stem Cells in Osteoporotic Rats
METTL3 promotes osteogenic differentiation of osteoporotic adipose‐derived stem cells and accelerates the repair of cranial defect areas in osteoporotic rats by activating the Wnt signalling pathway. ABSTRACT The treatment of postmenopausal osteoporosis (OP) presents a multifaceted challenge.
Hui Tang+8 more
wiley +1 more source
Intelligent Manufacturing for Osteoarthritis Organoids
Overall schematic of intelligent manufacturing in osteoarthritis organoids. Broad overview of the article's structure, outlining the progression from fundamental joint anatomy and OA pathogenesis to organoid construction and, ultimately, to intelligent manufacturing and future prospects.
Xukun Lyu, Jian Wang, Jiacan Su
wiley +1 more source
Large segmental bone defects can result in non‐union of fractures and present a formidable challenge in clinical management. This study aims to investigate the role of mechanical stimulation in regulating osteogenic differentiation of stem cells via the mechanosensitive protein PDLIM5, thereby promoting bone regeneration and repair.
Yuchao Yang+13 more
wiley +1 more source
Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration
Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen+9 more
wiley +1 more source
The proposed conceptual framework highlighting parents' central role in their child's healthcare experience. Abstract Aim To explore parents' experiences of family‐centered care (FCC) in a pediatric neurology clinic. Method In this explanatory sequential mixed‐methods study, parents of children with neurological conditions completed the Measure of ...
Ege Sarikaya+21 more
wiley +1 more source
Abstract Aims To explore the changes in bone mineral density (BMD) and body composition in patients after bariatric surgery using dual‐energy X‐ray absorptiometry (DXA) and quantitative computed tomography (QCT), analyse the relationships between these changes and weight loss, and the correlations between the parameters of DXA and QCT.
Xiaoqing Yuan+10 more
wiley +1 more source
Surgical Treatment for Multiple Unstable Uncomplicated Spinal Fractures in Children
Sergei V. Vissarionov+3 more
openalex +2 more sources
ABSTRACT Background/Aim This study evaluated the dentoalveolar responses of central incisors to anterior maxillary trauma in vitro and in silico using mouthguards (MGs) reinforced with polyamide mesh at three distinct positions. Material and Methods Forty 4‐mm thick MGs were categorized based on mesh location: Group MG1 + 3 (reinforcement 1 mm from the
Talita Suelen de Queiroz+5 more
wiley +1 more source