Results 131 to 140 of about 1,725,557 (355)

Reinstating Niche Failure in Diabetic Cranial Defects via Chronotaxic Signal‐Amplifying Fluidic Biomimetic Hydrogel

open access: yesAdvanced Science, EarlyView.
An in situ moldable GelSSO/PDA@SDF hydrogel functions as a chronotaxic signal‐amplifying biomimetic niche to restore regenerative failure in diabetic cranial defects. By sequentially releasing SDF‐1α‐loaded PDA nanoparticles and osteoinductive oligodeoxynucleotides, it orchestrates immunomodulation, progenitor recruitment, angiogenesis, and ...
Yingji Mao   +5 more
wiley   +1 more source

Mathematical model for predicting human vertebral fracture [PDF]

open access: yes, 1973
Mathematical model has been constructed to predict dynamic response of tapered, curved beam columns in as much as human spine closely resembles this form. Model takes into consideration effects of impact force, mass distribution, and material properties.
Benedict, J. V.
core   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

open access: yesAdvanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr.   +20 more
wiley   +1 more source

Human Evolution and Osteoporosis-Related Spinal Fractures

open access: yesPLoS ONE, 2011
The field of evolutionary medicine examines the possibility that some diseases are the result of trade-offs made in human evolution. Spinal fractures are the most common osteoporosis-related fracture in humans, but are not observed in apes, even in cases
Meghan M. Cotter   +4 more
semanticscholar   +1 more source

Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase

open access: yesAdvanced Science, EarlyView.
Overview of Sructure, Multienzyme‐mimicking Activity and Advanced Therapeutic Approach Based on LDHs–Mimetic Oxidoreductase. Abstract Redox dysregulation is recognized as a key driver in the pathophysiology of numerous refractory diseases, contributing significantly to the progression and poor prognosis.
Kai Song   +9 more
wiley   +1 more source

Kyphoplasty as a Treatment Option for Traumatic Burst Fractures: A Case Series Evaluating Patient Outcomes and Functional Benefits

open access: yesBrain Sciences
Background/Objectives: Kyphoplasty and vertebroplasty are minimally invasive approaches for spinal fractures aiming to reduce pain, increase mobilization, and prevent further vertebral height loss.
Anoop S. Chinthala   +5 more
doaj   +1 more source

Artificial Intelligence for Bone: Theory, Methods, and Applications

open access: yesAdvanced Intelligent Discovery, EarlyView.
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan   +3 more
wiley   +1 more source

Two Fractures of the Cervical Spine in Ankylosing Spondylitis 8 Years Apart

open access: yesJournal of Spinal Surgery
The cervical spine is the most common site of spinal fractures in patients with ankylosing spondylitis (AS). These fractures can occur either through the disc space or through the vertebral body itself.
Prasad Krishnan, Dimble Raju, Sayan Das
doaj   +1 more source

A Robot‐Assisted Remote Rehabilitation System for Ankle Fractures Based on Predictive Force and Full‐Cycle Training Strategy

open access: yesAdvanced Intelligent Systems, EarlyView.
This study presents a robot‐assisted remote rehabilitation system for postoperative ankle fractures. The 2.634 kg modular system uses wireless control and deep learning to predict force delays, achieving 100 Hz control (normalized root mean square error ≤ 10.89%).
Zhiyuan He   +4 more
wiley   +1 more source

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