Results 111 to 120 of about 103,162 (311)

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

Advanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su, Tianqing Nie, Guofeng Chen, Muya Xiong, Yumin Zhang, Guoqing Wu, Mengyuan You, Hang Xie, Jian He, Yanchao Xiong, Hangchen Hu, Wenfeng Zhao, Minjun Li, Gengfu Xiao, Leike Zhang, Yechun Xu   +15 more
wiley   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Can we predict post-surgical improvement in functional stooping in lumbar spinal stenosis? Insights from oblique lumbar interbody fusion outcomes and radiologic predictors [PDF]

Dong-Ho Kang, Jonghyuk Baek, Bong‐Soon Chang, Sam Yeol Chang, Dongook Kim, Sang Hyun Park, Hyoungmin Kim   +6 more
openalex   +1 more source

4D Printing of Magnetically Responsive Shape Memory Polymers: Toward Sustainable Solutions in Soft Robotics, Wearables, and Biomedical Devices

Advanced Science, EarlyView.
Merging 4D printing with magneto‐responsive shape memory polymers opens new avenues for intelligent, reconfigurable systems. This review navigates cutting‐edge fabrication techniques, magnetic fillers, and smart polymer matrices, unveiling their potential in soft robotics, biomedical devices, and wearable tech.
Kiandokht Mirasadi, Mohammad Amin Yousefi, Liuchao Jin, Davood Rahmatabadi, Majid Baniassadi, Wei‐Hsin Liao, Mahdi Bodaghi, Mostafa Baghani   +7 more
wiley   +1 more source

Spinal fusion surgery use among adults with low back pain enrolled in a digital musculoskeletal program: an observational study

BMC Musculoskeletal Disorders
Objectives To compare 12-month spinal fusion surgery rates in the setting of low back pain among digital musculoskeletal (MSK) program participants versus a comparison cohort who only received usual care.
Sandhya Yadav, Laura S. Gold, Qasim Hassan Zaidi, Raymond Hwang, Louie Lu, Grace Wang   +5 more
doaj   +1 more source

Fusion rate of a PEEK TLIF cage according to the addressed spinal segment - a retrospective analysis [PDF]

, 2018
Sukhan Jung, M Breitenfelder, Hiltrud Niggemann, Johannes Stöve, Ammar Qamar Ul Hasan   +4 more
openalex   +1 more source

Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids

Advanced Science, EarlyView.
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li, Jing Zhang, Lori Bulwith, Lee Niswander   +3 more
wiley   +1 more source

CORR Insights®: Is Growth-friendly Surgical Treatment Superior to One-stage Posterior Spinal Fusion in 9- to 11-year-old Children with Congenital Scoliosis?

, 2020
A. Noelle Larson
openalex   +2 more sources

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source

P0824 INTESTINAL FATTY ACID BINDING PROTEIN AND RISK OF ACUTE PANCREATITIS AFTER POSTERIOR SPINAL FUSION SURGERY [PDF]

, 2004
Zhaoping He, Pravin V. Jadhav, Dalal Tonb, T. Nadal, Frank E. Miller, Suken A. Shah, K. Dabney, R. Brenn, Mary C. Theroux, John McCloskey, Dhaval Mehta   +10 more
openalex   +1 more source