Results 151 to 160 of about 110,874 (309)

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

open access: yesAdvanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim   +2 more
wiley   +1 more source

THBS1+ Macrophages Exacerbate Modic Changes via SDC4‐Dependent Activation of NLRP3 Inflammasome

open access: yesAdvanced Science, EarlyView.
The illustration of THBS1+ macrophages exacerbate MCs via SDC4‐dependent activation of the NLRP3 inflammasome. THBS1+ macrophage subpopulation was identified in MCs through single‐cell RNA sequencing. C. acnes and its metabolites activate THBS1 expression in macrophages via the TLR signaling pathway.
Xiangxi Kong   +16 more
wiley   +1 more source

Smart Flexible Tactile Sensors: Recent Progress in Device Designs, Intelligent Algorithms, and Multidisciplinary Applications

open access: yesAdvanced Intelligent Discovery, EarlyView.
Flexible tactile sensors have considerable potential for broad application in healthcare monitoring, human–machine interfaces, and bioinspired robotics. This review explores recent progress in device design, performance optimization, and intelligent applications. It highlights how AI algorithms enhance environmental adaptability and perception accuracy
Siyuan Wang   +3 more
wiley   +1 more source

Investigating Cost Variation Within Spinal Fusion Payment Groups [PDF]

open access: yes, 2015
Background: Medicare reimbursement to hospitals for spinal fusion surgery is provided as a fixed payment for each admission based on Diagnosis Related Group (DRG).
Wright, David
core  

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

open access: yesAdvanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong   +5 more
wiley   +1 more source

Characteristics, Management, and Utilization of Muscles in Musculoskeletal Humanoids: Empirical Study on Kengoro and Musashi

open access: yesAdvanced Intelligent Systems, EarlyView.
Musculoskeletal humanoids exhibit rich biomechanical properties that remain insufficiently unified in prior discussions. This article systematically categorizes muscle characteristics into five properties: redundancy, independency, anisotropy, variable moment arm, and nonlinear elasticity, and analyzes their combined effects on control.
Kento Kawaharazuka   +2 more
wiley   +1 more source

DIGITAL PROCESSING FOR FLUOROSCOPY-BASED INTERVERTEBRAL KINEMATIC ANALYSIS

open access: yes, 2011
Spinal degenerations can lead to segmental instability that is regarded as a major cause of back pain and is often an important factor in deciding on surgical fusion or prosthesis implant.
Cerciello, Tommaso
core  

EMG‐Driven Telemetry and Inference System for Fish: Pose Reconstruction and Flow Sensing

open access: yesAdvanced Intelligent Systems, EarlyView.
This work introduces an electromyography (EMG)‐driven telemetry framework that reconstructs body pose and infers hydrodynamic conditions in freely swimming fish. A custom 16‐channel archival system records intramuscular EMG, enabling deep‐learning models to decode joint kinematics, classify flow regimes, and reveal channel‐efficient sensing strategies.
Rahdar Hussain Afridi   +7 more
wiley   +1 more source

One‐Shot Multimaterial 3D Printing of a Flexible Spine for a Robotic Fish Prototype

open access: yesAdvanced Intelligent Systems, EarlyView.
A one‐shot multimaterial 3D printing approach enables a monolithic soft robotic fish integrating a compliant spine and rigid vertebrae. Electromagnetic linear actuators drive tendon‐based transmission, producing controlled tail oscillations. Finite element modeling and experiments show strong agreement, while optimized material selection improves ...
Marco Colletta   +3 more
wiley   +1 more source

Reducing Preoperative Anxiety in Adolescents Facing Spinal Fusion Surgery

open access: yes, 2017
Reducing preoperative anxiety for adolescents facing spinal fusion surgery for the treatment of scoliosis has significant implications for clinical practice and patient outcomes for this specific population.
Parke, Anna Gayle
core  

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