Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis +4 more
wiley +1 more source
Perioperative Care of an Eleven-Year-Old Child With Osteogenesis Imperfecta Type II During Posterior Spinal Fusion. [PDF]
Soliman A +4 more
europepmc +1 more source
Biomaterial design strategies for enhancing mitochondrial transplantation therapy
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang +12 more
wiley +1 more source
A retrospective cohort analysis of robotic <i>vs</i>. non-robotic same day anterior posterior 1-2 level lumbar spinal fusion. [PDF]
Mo K +9 more
europepmc +1 more source
Clinical Images: Skeletal fluorosis presenting with diffuse periostitis and polyarticular synovitis
Arthritis &Rheumatology, EarlyView.
Mitali Sen
wiley +1 more source
Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma +9 more
wiley +1 more source
Mechanical stress on the rod in posterior spinal fusion with and without rod fracture: a finite element analysis. [PDF]
Inoue T +4 more
europepmc +1 more source
Clinical Images: Bone Buds as Precursors to Ankylosis in Axial Spondyloarthritis
Arthritis &Rheumatology, EarlyView.
Lilach Shkolnik Arad, Gleb Slobodin
wiley +1 more source
Marine silicon for biomedical sustainability
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han +3 more
wiley +1 more source

