Metagenomic next-generation sequencing for the clinical identification of spinal infection-associated pathogens [PDF]
Frontiers in Cellular and Infection MicrobiologyBackgroundThis study aimed to evaluate the efficacy of metagenomic next-generation sequencing (mNGS) technology for identifying pathogens associated with spinal infection (SI).MethodsA retrospective analysis was conducted on clinical data from 193 ...
Tengfei Shi +8 more
doaj +4 more sources
Application of metagenomic next-generation sequencing for rapid molecular identification in spinal infection diagnosis [PDF]
Frontiers in Cellular and Infection MicrobiologyObjectiveThis study aimed to determine the sensitivity and specificity of metagenomic next−generation sequencing (mNGS) for detecting pathogens in spinal infections and to identify the differences in the diagnostic performance between mNGS and targeted ...
Hui Lv +14 more
doaj +4 more sources
Percutaneous CT-guided or endoscopic spinal biopsy with accurate pathogen detection for spinal infection [PDF]
Frontiers in NeurologyAimsIn this study, we aimed to analyze the pathogen detection results in spinal infections using percutaneous CT-guided biopsy or transforaminal endoscopic spinal biopsy.MethodsThis is a retrospective observational study of patients who underwent biopsy ...
Jinmei Chen +7 more
doaj +2 more sources
Spinal infection caused by Aspergillus terreus in immunocompetent individuals: a case report and literature review [PDF]
Frontiers in MedicineSpinal infections, particularly those caused by Aspergillus terreus, represent complex and rare clinical challenges. They are even less common in patients with a normal immune system.
Lingling Liu +9 more
doaj +2 more sources
Diagnosis of Spinal Infection with Alpha-defensin Lateral Flow Test: A Preliminary Report [PDF]
Spine Surgery and Related Research, 2022 Introduction: The alpha-defensin lateral flow test has been used in periprosthetic joint infection as a diagnostic support tool because of its simplicity and speed. However, the test has not been used to diagnose spinal infections.
Atsuhiro Yoshida +5 more
doaj +2 more sources
Misdiagnosed with spinal infection instead of SAPHO syndrome: a case report and literature review [PDF]
Frontiers in ImmunologyThis article reports a case of SAPHO syndrome misdiagnosed as spinal infection, detailing the clinical manifestations, laboratory tests, and imaging features of the patient.
Shuai Wang, Shiyong Wan, Zhengqi Chang
doaj +2 more sources
Improved accuracy of etiological diagnosis of spinal infection by metagenomic next-generation sequencing [PDF]
Frontiers in Cellular and Infection Microbiology, 2022 Currently, the use of metagenomic next-generation sequencing (mNGS), a new approach to identify organisms in infectious diseases, is rarely reported in the diagnosis of spinal infection.
Liang Xu +6 more
doaj +2 more sources
Spinal infection caused by Aspergillus flavus in a diabetic: a case report and literature review [PDF]
Frontiers in MedicineSpinal infections, notably those induced by Aspergillus flavus (A. flavus), represent a complex and uncommon clinical challenge. In individuals with diabetes mellitus, the risk is exacerbated due to a compromised immune response and a heightened ...
Hongtao Li +5 more
doaj +2 more sources
Хирургия позвоночника, 2023 Objective. To present a brief description of a series of clinical cases of infectious spondylodiscitis with an assessment of the used diagnostic criteria in terms of their influence on the choice of sanifying treatment tactics. Material and Methods.
Lyudmila V. Lyubimova +4 more
doaj +1 more source
Journal of Neurological Surgery Part A: Central European Neurosurgery, 2022 Pyogenic spinal infection (spondylodiscitis) is a life-threatening medical condition. Over the past three decades, its incidence has increased 15-fold. This is in part due to the aging of the population, increase in immunocompromised patients, and better diagnostic abilities.
Bawarjan Schatlo, Ehab Shiban
openaire +4 more sources