Results 91 to 100 of about 138,660 (303)

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Transforaminal epidural steroid injection under computed tomography guidance in relieving lumbosacral radicular pain

Acta Orthopaedica et Traumatologica Turcica, 2021
Objectives: We analyzed the efficacy of transforaminal epidural steroid injections under computed tomography (CT) in relieving lumbosacral radicular pain due to spinal stenosis.\nMethods: Forty-two patients (7 males, 35 females; mean age 67 years; range ...
Oguz Karaeminogullari, Orcun Sahin, Fatih Boyvat, Rahmi Can Akgun, Utku Gurun, Huseyin Demirors, Ismail Cengiz Tuncay, Reha N. Tandogan   +7 more
doaj  

Forebrain Origins of Glutamatergic Innervation to the Rat Paraventricular Nucleus of the Hypothalamus: Differential Inputs to the Anterior Versus Posterior Subregions [PDF]

, 2011
The hypothalamic paraventricular nucleus (PVN) regulates numerous homeostatic systems and functions largely under the influence of forebrain inputs. Glutamate is a major neurotransmitter in forebrain, and glutamate neurosignaling in the PVN is known to ...
Cullinan, William E, Herman, James P., Jones, Kenneth R., Ulrich-Lai, Yvonne M., Ziegler, Dana R.   +4 more
core   +3 more sources

Soft Ionic and Electronic Triboelectric Nanogenerators: Toward Attachable and Implantable Biomedical Applications

Advanced Materials, EarlyView.
This review provides an overview of triboelectric nanogenerator (TENG)–based biomedical applications by classifying studies into electronic and ionic systems across attachable and implantable platforms. It summarizes key material choices, device structures, and working mechanisms that characterize current TENG‐based research, and outlines six future ...
Kyongtae Choi, Jimin Park, Won Jun Song, Soohwan An, Seonggyu Choe, Byeong‐Rak Keum, Min Young Kim, Dae Hee Hwang, Young‐Geun Park, Sung‐Won Kim, Sangyul Baik, Gwang‐Bum Im, Younghoon Lee   +12 more
wiley   +1 more source

The Absence of the Leukotriene B Receptor BLT1 Attenuates Peripheral Inflammation and Spinal Nociceptive Processing Following Intraplantar Formalin Injury

Molecular Pain, 2015
Background Leukotriene B 4 (LTB 4 ) is a potent lipid mediator of inflammation, and its biological effects are mediated primarily through the high affinity LTB 4 receptor BLT1.
Miho Asahara, Nobuko Ito, Takehiko Yokomizo, Motonao Nakamura, Takao Shimizu, Yoshitsugu Yamada   +5 more
doaj   +1 more source

Effects of guanidine on synaptic transmission in the spinal cord of the frog [PDF]

, 1977
The effects of guanidine on motoneurons of the isolated frog spinal cord were studied by adding the drug to the solution bathing the cord during intracellular recording. Guanidine (5·10–4 M) did not alter the membrane potential of motoneurons.
A. K�hner, B. Katz, E. Gergens, E. H. Lambert, F. Colomo, F. H. Norris, H. Ter�v�inen, J. I. Simpson, K. Koizumi, K. Ricker, M. A. Kamenskaya, M. A. Kamenskaya, M. Otsuka, P. Grafe, R. C. Scaer, S. D. Erulkar, S. J. Oh, U. Sonnhof, U. Sonnhof, W. C. Wiederholt   +19 more
core   +1 more source

Fabric‐Based Wearable Robotic Exoskeleton Gloves: Advancements and Challenges

Advanced Materials Technologies, EarlyView.
This review highlights interdisciplinary technological advances in fabric‐based robotic gloves, focusing on progress in design, fabrication, actuation, sensing, control, and power and energy requirements. It also addresses performance testing and validation, including biomechanical, strength, functional, user experience, and durability assessments, to ...
Ayse Feyza Yilmaz, Gökhan Ince, Ozgur Atalay   +2 more
wiley   +1 more source

Anatomical and molecular properties of long descending propriospinal neurons in mice [PDF]

, 2017
Long descending propriospinal neurons (LDPNs) are interneurons that form direct connections between cervical and lumbar spinal circuits. LDPNs are involved in interlimb coordination and are important mediators of functional recovery after spinal cord ...
Boyle, Kieran, Callister, Robert J., Conn, Victoria, Flynn, Jamie R., Goulding, Martyn D., Graham, Brett A., Hughes, David I., Velasquez, Tomoko, Watanabe, Masahiko   +8 more
core   +1 more source

Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy

Advanced Robotics Research, EarlyView.
Robotic materials are playing an increasingly vital role in enabling sensing and actuation at small scales. This perspective highlights recent advances in magnetic materials and magnetically actuated devices for wireless sensing, actuation, and energy harvesting toward implantable robotic systems for closed‐loop therapy.
Yusheng Wang, Ruijian Ge, Xiaoguang Dong
wiley   +1 more source

Ultrasound-guided caudal epidural injection to treat symptoms of lumbar spinal stenosis: a retrospective study

European Journal of Translational Myology
Lumbar spinal stenosis (LSS) occurs when bony, ligamentous, and synovial elements of the lower axial spine degenerate and overgrow, compressing neural and vascular elements in the spinal canal.
Veronica Gagliardi, Antonello Lovato, Francesco Ceccherelli, Giuseppe Gagliardi   +3 more
doaj   +1 more source