Results 121 to 130 of about 88,525 (289)

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

De-implementing Spinal Injections in Pursuit of Value-Based Care: Rethinking Pain Relief. [PDF]

J Pain
Ballengee LA, Lentz TA, Goertz C, McStay F, Morken I, George SZ.   +5 more
europepmc   +1 more source

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source

Single Intraperitoneal Injection of Low-Dose Ketamine Pretreatment Alleviates Mechanical Hyperalgesia and Downregulates the Expression of Inflammatory Cytokines in Spinal Dorsal Horn of Rats

, 2015
Xu Li, Yu Shen, Lin Liu, Yin Cui, Xiaoping Gu, Zhengliang Ma   +5 more
openalex   +1 more source

Is retirement a pain in the back? A 23-year population-based study on the impact of age and employment on spinal injections. [PDF]

Neuroradiol J
Faghani S, Moassefi M, McDonald JS, Erickson BJ, Benson JC.   +4 more
europepmc   +1 more source

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

Effectiveness of transforaminal steroid injections in spinal canal stenosis grade 1 to 3

Introduction: Transforaminal injections have been associated with rare but major complications. Despite several studies on epidural steroid injection as a minimally invasive non-surgical method to relieve the pain of spinal canal stenosis, there is no ...
Mahmoodkhani, M., Donya Sheibani Tehrani, Rezvani, M., Navid Hajiabbasi, M., Askariardehjani, N., Mohammad Navid Hajiabbasi, Sheibani Tehrani, D., Mehdi Mahmoodkhani, Navid Askariardehjani, Majid Rezvani   +9 more
core   +1 more source

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

Advanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo, Hongju Xiao, Shenghao Ba, Yu Zhou, Bijun Wang, Bin Yu, Yufeng Huang, Haihong Zhao, Zhefan Stephen Chen, Na Shen, Zhaoyu Ba, Desheng Wu   +11 more
wiley   +1 more source

Perspective: Risks/adverse events for epidural spinal injections. [PDF]

Surg Neurol Int
Epstein NE, Agulnick MA.
europepmc   +1 more source