Results 161 to 170 of about 494,812 (295)

Ultrasound-guided Caudal Epidural Pharmacopuncture Injection and Comprehensive Korean Medical Treatment for Spinal Stenosis: A Case Report

Journal of Acupuncture Research
The present case report evaluated the effects of ultrasound-guided caudal epidural pharmacopuncture injection combined with integrative Korean medicine treatment on pain relief and functional recovery in a patient with spinal stenosis.
Gi-Tae Park, Myung-In Jeong, Hyun-Il Jo, Cheol-Ju Kim, Jung-Hyun Kim, Eun-Yul Han   +5 more
doaj   +1 more source

Design and Evaluation of a Needle Manipulation System with EM Tracking for CT-Guided Spinal Injections. [PDF]

Int Symp Med Robot
Chang C, Mei J, Wang Y, Al-Zogbi L, Leonard S, Jain A, Iordachita I.   +6 more
europepmc   +1 more source

Dual‐Gene Edited Extracellular Vesicles Remodel the Redox Homeostasis to Inhibit Ferroptosis in Intervertebral Disc Degeneration

Advanced Science, EarlyView.
ABSTRACT Intervertebral disc degeneration (IDD) is driven by ferroptosis of nucleus pulposus cells (NPCs) as a core pathological mechanism. Nucleus pulposus progenitor cells (NPPCs), exhibiting stem cell‐like properties, yield extracellular vesicles (PEVs) with high affinity for NPCs and enable targeted phenotypic regulation.
Jing Yan, Yazhou Lin, Shuo Miao, Minghao Chao, Chengbai Dai, Ziwen Hao, Rui Chen, Ming Guan, Bin Pan, Fenglei Gao, Quan Zhou   +10 more
wiley   +1 more source

Perspective: Risks/adverse events for epidural spinal injections. [PDF]

Surg Neurol Int
Epstein NE, Agulnick MA.
europepmc   +1 more source

In Vivo Direct Reprogramming: Current Progress and Future Prospects from Mechanisms to Therapeutic Application

Advanced Science, EarlyView.
This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh, Mauro Calvoli, Kyeong Kyu Kim   +2 more
wiley   +1 more source

Study of effectiveness of bronchial clearence in subjects with upper spinal cord injuries. Examination of a rehabilitation programme involving mechanical insufflation and exsufflation

, 2004
Study design: this randomized controlled trial designed to establish the effectiveness of mechanical insufflation and exsufflation in post-tracheostomy subjects with upper spinal cord injuries (C1-C7), ASIA A classification and bronchial hypersecretion.
PILLASTRINI, PAOLO, BORDINI S., MENARINI, MAURO   +2 more
core  

ACSL4‐Dependent Lysosomal Lipid Peroxidation Links WTAP‐Mediated m6A Modification to Intervertebral Disc Degeneration

Advanced Science, EarlyView.
IL‐1β upregulates the protein level of WTAP, which promotes the m6A modification of ACSL4 mRNA in an IGF2BP2‐dependent manner, thereby enhancing its stability. The increased ACSL4 drives lipid peroxidation, leading to lysosomal membrane permeabilization (LMP) and impaired mitophagy, which collectively accelerate intervertebral disc degeneration (IVDD).
Shu Jia, Xu Gao, Laimin Zhu, Haixia Song, Jing Wu, Shang Chen, Sheng Gao, Lu Zhang, Chunyang Meng   +8 more
wiley   +1 more source

Simulation-based Flexible Needle Control with Single-core FBG Feedback for Spinal Injections. [PDF]

IEEE Trans Med Robot Bionics
Wang Y, Xu Y, Kang J, Fritz J, Iordachita I.   +4 more
europepmc   +1 more source

Restoration of m6A‐Modified circPSMB1 Suppresses Chordoma Progression and Enables Local Nanotherapeutic Intervention

Advanced Science, EarlyView.
An m6A‐modified circRNA, circPSMB1, is identified as a tumor suppressor in chordoma. METTL3‐dependent m6A promotes circPSMB1 interaction with HNRNPA2B1, limiting c‐MYC expression and malignant progression. An injectable HMnO2‐based nanohydrogel enables local circPSMB1 delivery and tumor microenvironment‐responsive therapy, offering a promising strategy
Yingchuang Tang, Liang Qiu, Xingbang Ruan, Yihan Shi, Ye Wang, Hanwen Li, Kai Zhang, Kangwu Chen   +7 more
wiley   +1 more source

The role of spinal injections towards optimizing patient selection for spinal surgery: A proof-of-concept study in 176 lower back pain patients. [PDF]

Patient Saf Surg
Voelker A, Kroboth K, Heyde CE.
europepmc   +1 more source