Results 51 to 60 of about 202,601 (255)

Spinal injury in underbody blast [PDF]

, 2016
Improvised Explosive Device (IED) is common in insurgent conflict as such devices are cheap, available, and devastating. Recent literature shows that victims of these devices often have complex injuries including spinal fractures.
Spurrier, Edward James
core   +1 more source

Biological and Mechanical Limitations for Chronic Fast‐Scan Cyclic Voltammetry Sensor Design

Advanced Materials Technologies, EarlyView.
Real‐time detection of neurochemicals has demonstrated value in the field of neuroscience. However, current methods have limitations for use in the chronic setting, which is often the ideal environment for research. This article discusses these limitations, as well as technologies that have been developed to overcome them, and provides recommendations ...
Mason L. Perillo, Bhavna Gupta, Akash Saxena, Alexandra P. Veltri, Wen Li, James R. Siegenthaler, Erin K. Purcell   +6 more
wiley   +1 more source

Knowledge, attitudes and practices of medical staff towards obesity management in patients with spinal cord injuries: an International survey of four western European countries [PDF]

, 2014
Objective: To (1) examine the opinions of medical staff working in spinal cord injury (SCI) centres (SCICs); (2) evaluate their knowledge, attitudes and practices towards obesity prevention and management; (3) report the number of beds and dietitians ...
Belci, M, Forbes, A, Hirani, S P, Roels, E, Smith, É, van Middendorp, J, van Nes, I, Wong, S   +7 more
core   +1 more source

Vertical Membrane‐Free Organ‐on‐a‐Chip for High‐Throughput In Vitro Studies and Drug Screening

Advanced Materials Technologies, EarlyView.
This novel microfluidic organ‐on‐a‐chip (OoC) platform enables cost‐effective, high‐throughput in vitro modeling. With vertical compartmentalization and gravity‐driven flow, it eliminates porous membranes and external pumps. Successfully generating intestine, cartilage, and tendon models, this study demonstrates drug responses, including 5‐fluorouracil
Xavier Barceló, Pooya Azizian, Blanca del Pozo, Marta Olle‐Monge, Lourdes Gombau, Joan M. Cabot   +5 more
wiley   +1 more source

A Bistable Assistive Device for Wireless Control of a Dysfunctional Bladder Under Minimal Stress

Advanced Materials Technologies, EarlyView.
This paper presents a wireless system designed to restore bladder function in patients with an underactive bladder (UAB). The system features a multilayered structure, combining a pre‐shaped restoration layer with a spring‐based actuator. The system delivers 95–100% voiding efficiency within a 10‐s activation while ensuring minimal stress on the ...
Shujun Xiao, Kieran Holmes‐Martin, Lichang Zhu, Alberto Pirrera, Faezeh Arab Hassani   +4 more
wiley   +1 more source

Multifunctional Fibrous Mats: Stretchable, Conductive, and Hydrophilic Platforms for Wearable Electronics

Advanced Materials Technologies, EarlyView.
A hydrophilic, stretchable, nonwoven electrospun fiber mat targeted to be applied in long‐term bioelectronic devices. By incorporating amphiphilic polyethylene glycol block copolymers in a polydimethylsiloxane matrix, the material develops stable hydrophilicity, enhanced breathability, as well as enhanced adhesion to cells.
Joab S. Dorsainvil, Jafar Batayneh, Maya McDonald, Natalie Pachter, Serena Patel, Dana Manashirov, Tracy Hookway, Ahyeon Koh   +7 more
wiley   +1 more source

Role of peripheral quantitative computed tomography in identifying disuse osteoporosis in paraplegia [PDF]

, 2009
Objective: Disuse osteoporosis is a major long-term health consequence of spinal cord injury (SCI) that still needs to be addressed. Its management in SCI should begin with accurate diagnosis, followed by targeted treatments in the most vulnerable ...
A Frotzler, A Frotzler, AA Freehafer, Alan N. McLean, B Chen, David B. Allan, ED Bruin de, HH Bolotin, HM Frost, J Rittweger, JL Ferretti, L Giangregorio, L Maimoun, M Bélanger, P Eser, P Eser, P Eser, P Frey-Rindova, P Vestergaard, S Dudley-Javoroski, S-D Jiang, Sylvie Coupaud, T Mohr   +22 more
core   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

A model for incorporating a clinically-feasible exercise test in paraplegic annual reviews : a tool for stratified cardiopulmonary stress performance classification and monitoring [PDF]

, 2013
To identify and characterize an exercise test for use in routine spinal cord injury clinical review, and (ii) to describe levels of, and factors affecting, cardiopulmonary stress performance during exercise in the chronic paraplegic population in ...
Allan, David B., Berry, Helen, Coupaud, Sylvie, Grant, Stanley, McLean, Alan N.   +4 more
core   +1 more source

Immune Checkpoint PD‐L1 Modulates Retinal Microglial Activation to Alleviate Vascular Leakage in Choroidal Neovascularization via ERK

Advanced Science, EarlyView.
PD‐L1 limits neuroinflammation in neovascular AMD by modulating microglial activation. Its deficiency exacerbates vascular leakage and choroidal neovascularization (CNV) via ERK signaling, while enhancing PD‐L1 reduces inflammation and neovascularization. Targeting PD‐L1 may offer a novel immunomodulatory strategy for NVAMD.
Yue Zou, Junliang Jiang, Yunqin Li, Xinyi Ding, Qiuping Tong, Ying Shi, Lei Xiao, Ling Chen   +7 more
wiley   +1 more source