Results 61 to 70 of about 1,138,451 (355)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Chronic non-specific low back pain - sub-groups or a single mechanism? [PDF]

, 2008
Copyright 2008 Wand and O'Connell; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use ...
A Antal, A Antal, A Delitto, A Keller, A Moore, A Pascual-Leone, A Radebold, A Radebold, A Rosner, A Schrag, AF Bendix, AF Mannion, AF Molsberger, AH McGregor, AJ Harris, AV Apkarian, AV Apkarian, AWM Evers, B Kainz, B Schweikert, Benedict Martin Wand, BF Walker, BW Koes, BW Koes, C Eccleston, C Larivie're, C Leboeuf-Yde, C Leboeuf-Yde, C Maihöfner, C Maihöfner, C Richardson, C Schmahl, C Young-Casey, CJ Hsieh, CJ Lamoth, CJ Main, CJ Main, CJ McCarthy, CJ McCarthy, CPN Watson, CS McCabe, CS McCabe, D Turk, DA Seminowicz, DC Turk, DG Wilder, DI Cook, DJ Clauw, DJ Critchley, DL Riddle, DM Small, EE Bostan, EH Kääpä, EI Skargren, EJ Carragee, EJ Carragee, EL Hurwitz, EL Hurwitz, EM Hay, EM Wassermann, F Fregni, F Keefe, F Kleinstück, FJ Keefe, G Bronfort, G Jull, G Waddell, GA Koumantakis, GE Bekkering, GE Hicks, GL Moseley, GL Moseley, GL Moseley, GL Moseley, GL Moseley, GL Moseley, GR Fink, H Flor, H Flor, H Flor, H Flor, H Flor, H Flor, H Frost, H Merskey, HJM Van Den Hoogen, ID Grachev, ID Grachev, ID Grachev, J Lorenz, J McCarthy, J Pells, JA Hayden, JA Hayden, JD Childs, JE Cassisi, JG Klein, JH Van Dieën, JL Carr, JL Porter, JM Fritz, JM Whitman, JS Lewis, JWS Vlaeyen, JWS Vlaeyen, KJ Petrie, KP Barr, KP Gill, L Klenerman, L Niemistö, L Vogt, LA Smith, LHM Pengel, LM McCracken, LM Smedstad, M Adams, M Jeannerod, M Leeuw, M Riipinen, M Van Der Hulst, M Van Tulder, M Yeh, MA Rogers, MC Cairns, MD Freeman, MD Grabiner, ME Geisser, MIV Mientjes, MN Baliki, MR Underwood, MS George, MW van Tulder, MW van Tulder, N Bogduk, N Bogduk, N Jousset, N Maniadakis, N Nies, Neil Edward O'Connell, NJ Zimny, NW Mok, P Dolan, P Jellema, P Kent, P Michaelson, P O'Sullivan, PB Fitzgerald, PB O'Sullivan, PB O'Sullivan, PH Canter, PH Ferreira, PJ Siddall, PJ Watson, PM Kent, R Andenaes, R Herbert, R Waxman, RA Deyo, RA McKenzie, RC de Charms, RJEM Smeets, RW Ostelo, RW Selles, S Brumagne, S Luoto, S Luoto, S Luoto, S Taimela, S Taimela, S Thompson, S Yusuf, SA Ferguson, SJ Linton, SJ Linton, SM Ott, T Bendix, T Flynn, T Giesecke, T Giesecke, T Honda, T Hyphantis, T Petersen, T Peterson, T Pincus, T Pincus, T Schmidt-Wilcke, The UK BEAM Trial Team, TS Carey, TZ Kincses, V Leinonen, VS Ramachandran, W Dankaerts, WJJ Assendelft, WO Spitzer, WS Marras, WS Marras, WS Marras, WS Marras, WS Marras   +198 more
core   +4 more sources

The regional effect of spinal manipulation on the pressure pain threshold in asymptomatic subjects: a systematic literature review

Chiropractic & Manual Therapies, 2018
BackgroundSpinal manipulation (SM) has been shown to have an effect on pain perception. More knowledge is needed on this phenomenon and it would be relevant to study its effect in asymptomatic subjects.ObjectivesTo compare regional effect of SM on ...
Margaux Honoré, C. Leboeuf‐Yde, O. Gagey   +2 more
semanticscholar   +1 more source

Actionable Wearables Data for the Neurology Clinic: A Proof‐of‐Concept Tool

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Wearable devices can monitor key health and fitness domains. In multiple sclerosis (MS), monitoring step count and sleep is feasible, valid, and offers a holistic glimpse of patient functioning and worsening. However, data generated from wearables are typically unavailable at the point of care.
Nicolette Miller, Ebenezer Chinedu‐Eneh, Jaeleene Wijangco, Kyra Henderson, Nikki Sisodia, Narender Sara, Jennifer Reihm, Shane Poole, Jim Rowson, Chu‐Yueh Guo, Jeffrey M. Gelfand, Valerie J. Block, Riley Bove   +12 more
wiley   +1 more source

Treatment of Acute Sciatica [PDF]

, 2007
In patients with acute sciatica, bed rest and advice to stay active have similar outcomes on their functional status and perceived improvement. (Strength of Recommendation [SOR]: A) Spinal manipulation increases improvement compared with placebo; also ...
Dhillon, Baldev Singh, Markova, Tsveti, Martin, Sandra I.   +2 more
core  

In-home and remote use of robotic body surrogates by people with profound motor deficits [PDF]

, 2019
By controlling robots comparable to the human body, people with profound motor deficits could potentially perform a variety of physical tasks for themselves, improving their quality of life.
Grice, Phillip M., Kemp, Charles C.
core   +3 more sources

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

The effects of chiropractic spinal manipulation on central processing of tonic pain - a pilot study using standardized low-resolution brain electromagnetic tomography (sLORETA)

Scientific Reports, 2019
The objectives of the study were to investigate changes in pain perception and neural activity during tonic pain due to altered sensory input from the spine following chiropractic spinal adjustments.
M. S. Navid, D. Lelic, I. Niazi, Kelly Holt, E. Mark, A. Drewes, H. Haavik   +6 more
semanticscholar   +1 more source

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source

Conservative management of low back pain [PDF]

, 2001
Back pain is prevalent worldwide, but back pain disability has reached epidemic proportions in many industrialised societies. Few patients have serious medical pathology or direct neurological involvement requiring surgery.
De Souza, LH, Frank, AO
core