Results 131 to 140 of about 2,481 (285)

Spinal Stenosis: An Emerging Complication of Ageing in People With Haemophilia

Haemophilia, EarlyView.
ABSTRACT Introduction Advances in haemophilia care have brought the challenges of ageing for people with haemophilia (PWH) to the forefront. Age‐related spinal degeneration may result in spinal stenosis; however, the rates in PWH are unknown. We sought to systematically review Irish PWH to address this gap in the current literature.
Claire Kelly, Mark McGowan, Niamh Larkin, Jake M. Mc Donnell, Anne‐Marije Hilshof, Mary Byrne, Catherine Bergin, Aine O'Gara, Kevin Ryan, Mairead O'Donovan, Niamh O'Connell, Keith Synnott, Joseph S. Butler, Stacey Darwish, Brian O'Mahony, Megan Kennedy, Peter L. Turecek, James S. O'Donnell, John Gormley, Michelle Lavin   +19 more
wiley   +1 more source

The Utility of Different Approachs to Developing Health Utilities Data in Childhood Rare Diseases – A Case Study in Spinal Muscular Atrophy (SMA)

, 2017
Robin Thompson, Shalvaree Vaidya, Megan Teynor   +2 more
openalex   +1 more source

PRO23 HEALTHCARE RESOURCE UTILIZATION OVER THREE YEARS AMONG LATER CHILDHOOD, ADOLESCENT AND ADULT SPINAL MUSCULAR ATROPHY PATIENTS: A NATURAL HISTORY STUDY WITHIN U.S. HOSPITALS [PDF]

, 2019
Angela D. Paradis, Christina L. Wassel, Jill Dreyfus, Sandra P. Reyna, Nicole B. Johnson, Miral D. Jhaveri   +5 more
openalex   +1 more source

Cyclin‐dependent kinase 13 is indispensable for normal mouse heart development

Journal of Anatomy, Volume 246, Issue 4, Page 616-630, April 2025.
Congenital heart disease (CHD) is the most common defect in live births. The role of cyclin‐dependent kinase (CDK13) in cardiogenesis and CHD was studied using a transgenic mouse model (Cdk13tm1b) carrying deletion of exons 3 and 4, causing loss of function.
Qazi Waheed‐Ullah, Anna Wilsdon, Aseel Abbad, Sophie Rochette, Frances Bu'Lock, Asma Ali Saed, Marc‐Phillip Hitz, J. David Brook, Siobhan Loughna   +8 more
wiley   +1 more source

Sleep Medicine—What's in a Name?

Journal of Sleep Research, EarlyView.
ABSTRACT Sleep medicine has matured into a recognised medical discipline, characterised by defined diagnostic concepts, evidence‐based treatments, and significant progress in understanding sleep physiology and disorders. Sleep and its disturbances impact virtually every aspect of health and well‐being.
Dirk A. Pevernagie, Erna Sif Arnardottir, Oliviero Bruni, Sarah Hartley, Gert Jan Lammers, Tiina Paunio, Dieter Riemann, Renata L. Riha   +7 more
wiley   +1 more source

Diet in Pregnancy: A Review of Current Challenges and Recommendations. A British Nutrition Foundation Briefing Paper

Nutrition Bulletin, EarlyView.
ABSTRACT Pregnancy is a crucial period during which maternal nutrition, weight and lifestyle behaviours have a direct impact on both maternal and fetal health. This briefing paper describes dietary and lifestyle recommendations for women during the preconceptional period and throughout pregnancy, identifying specific factors that can be modified to ...
Kathryn H. Hart, Alyson J. Hill, Javier T. Gonzalez, Anne de la Hunty, Alison M. Gallagher, Sara A. Stanner   +5 more
wiley   +1 more source

Dominant spinal muscular atrophy with lower extremity predominance

Neurology, 2010
M. Harms, P. Allred, Robert Gardner, J. F. Filho, J. Florence, Alan Pestronk, M. Al-Lozi, R. Baloh   +7 more
semanticscholar   +1 more source

Phenotyping Neurodisability in Hospital Records in England: A National Birth Cohort Using Linked Administrative Data

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Children with neurodisability often have complex healthcare and educational needs. Evidence from linked administrative health and education data could improve joint working between services. Objective To develop a diagnostic code list to identify neurodisability in hospital admission records; to assess the representativeness of this
Ania Zylbersztejn, Philippa Rees, Rashmi D'Souza, Stuart Logan, Ayana Cant, Laura Gimeno, Vincent Nguyen, Jugnoo Rahi, Ruth Gilbert, Katie Harron, on behalf of HOPE Study, Bianca De Stavola, Lorraine Dearden, Johnny Downs, William Farr, Tamsin Ford, Kate Lewis, Matthew Lilliman, Jacob Matthews, Jennifer Saxton, Isaac Winterburn, Ruth Blackburn, Milagros Ruiz, Matthew Jay, Tony Stone, Farzan Ramzan   +25 more
wiley   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Exploring the respiratory efficacy of combined chronic glucocorticoid and antioxidant interventions in the mdx mouse: The PREDNAC trial

Experimental Physiology, EarlyView.
Abstract Duchenne muscular dystrophy (DMD) is characterized by respiratory muscle injury and weakness, ultimately leading to respiratory failure. Impaired respiratory muscle performance, fibrosis and inflammation in early disease are evident in the dystrophin‐deficient mdx mouse model of DMD.
Michael N. Maxwell, Ben T. Murphy, Fiona B. McDonald, Ken D. O'Halloran   +3 more
wiley   +1 more source