Results 141 to 150 of about 2,725,444 (278)

The Role of Adipokines in Spinal Disease: A Narrative Review

JOR SPINE, Volume 8, Issue 2, June 2025.
Adipokines, bioactive molecules secreted by adipose tissue, play a key role in both physiological regulation and disease pathogenesis. While their involvement in various organ systems is well documented, their role in spinal pathology remains underexplored.
Jake M. McDonnell, Stacey Darwish, Joseph S. Butler, Conor T. Buckley   +3 more
wiley   +1 more source

Brucella canis in two juvenile labrador retriever littermates with no known travel history

Veterinary Record Case Reports, Volume 13, Issue 2, June 2025.
Abstract Two labrador retriever littermates presented separately to investigate chronic lethargy and shifting lameness. In both cases, clinical examination revealed a multi‐limb lameness. Neither the patients nor their dam or sire had a travel history outside the UK.
Amy Lord, Oliver Russell, Ombeline McGregor, Robert Dudley, Cassia Hare, Barbara Skelly   +5 more
wiley   +1 more source

Genetic Determination of Motor Neuron Disease and Neuropathy [PDF]

, 2015
Following the completion of the Human Genome Project, a lot of progress has been made in understanding the genetic basis of motor neuron diseases (MNDs) and neuropathies.
Pavle Vrebalov Cindro, Veselin Vrebalov Cindro   +1 more
core   +1 more source

The Utility of Different Approachs to Developing Health Utilities Data in Childhood Rare Diseases – A Case Study in Spinal Muscular Atrophy (SMA)

, 2017
Robin Thompson, Shalvaree Vaidya, Megan Teynor   +2 more
openalex   +1 more source

PRO23 HEALTHCARE RESOURCE UTILIZATION OVER THREE YEARS AMONG LATER CHILDHOOD, ADOLESCENT AND ADULT SPINAL MUSCULAR ATROPHY PATIENTS: A NATURAL HISTORY STUDY WITHIN U.S. HOSPITALS [PDF]

, 2019
Angela D. Paradis, Christina L. Wassel, Jill Dreyfus, Sandra P. Reyna, Nicole B. Johnson, Miral D. Jhaveri   +5 more
openalex   +1 more source

Neural Metabolic Networks: Key Elements of Healthy Brain Function

Journal of Neurochemistry, Volume 169, Issue 6, June 2025.
This review originated from the Fourth International Society for Neurochemistry (ISN) and Journal of Neurochemistry (JNC) Flagship School (2022). Here, we describe how the specific bioenergetic profiles and metabolic exchanges between brain cells enable and gate synaptic function and behavior. Then, based on this analysis, we discuss the potential role
Nimrod Madrer, Nirma D. Perera, Nonthué A. Uccelli, Alice Abbondanza, Jens V. Andersen, Emma Veronica Carsana, Matthew D. Demmings, Regina F. Fernandez, Matheus Garcia de Fragas, Ismail Gbadamosi, Divita Kulshrestha, Ricardo A. S. Lima‐Filho, Oana C. Marian, Kia H. Markussen, Andrew J. McGovern, Elliott S. Neal, Sukanya Sarkar, Eva Šimončičová, Jazmín Soto‐Verdugo, Sozerko Yandiev, Ignacio Fernández‐Moncada   +20 more
wiley   +1 more source

AI and Deep Learning for Automated Segmentation and Quantitative Measurement of Spinal Structures in MRI [PDF]

arXiv
Background: Accurate spinal structure measurement is crucial for assessing spine health and diagnosing conditions like spondylosis, disc herniation, and stenosis. Manual methods for measuring intervertebral disc height and spinal canal diameter are subjective and time-consuming.
arxiv  

An anatomical investigation of alkaptonuria: Novel insights into ochronosis of cartilage and bone

Journal of Anatomy, Volume 246, Issue 6, Page 1053-1074, June 2025.
Examination of an alkaptonuria body highlights the susceptibility of all cartilage types and associated perichondrium to ochronotic pigmentation and the heterogeneity of ochronotic pigment distribution both within and between tissues. In joints, calcified cartilage pigments before non‐calcified cartilage.
Juliette H. Hughes, Gemma Charlesworth, Amanda Prior, Claire M. Tierney, Paul D. Rothwell, Neil P. Thomas, Lakshminarayan R. Ranganath, James A. Gallagher, Alistair P. Bond   +8 more
wiley   +1 more source

Measuring what really matters: Why developing patient‐reported outcome measures in Duchenne muscular dystrophy should involve patients and caregivers

Developmental Medicine &Child Neurology, Volume 67, Issue 7, Page 832-833, July 2025.
Sebastian Friedrich, Gudrun Reeskau, Joachim Sproß, Thorsten Langer   +3 more
wiley   +1 more source

15. Cluster Headache

Pain Practice, Volume 25, Issue 5, June 2025.
ABSTRACT Introduction Cluster headache is a rare primary headache disorder characterized by excruciating unilateral pain around the eye, lasting between 15 and 180 min, accompanied by ipsilateral cranial autonomic symptoms. Cluster headache is classified into two forms: episodic and chronic, with chronic cluster headache defined by pain‐free intervals ...
Casper S. Lansbergen, Rolf Fronczek, Leopoldine A. Wilbrink, Steven P. Cohen, Cecile C. de Vos, Frank J. P. M. Huygen   +5 more
wiley   +1 more source