Results 101 to 110 of about 97,266 (336)

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐modifying Antirheumatic Drug

Arthritis Care &Research, Accepted Article.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD) Methods PrismRA incorporated 19 gene expression features and 4 clinical features to assess a patient's likelihood of ...
Fenglong Xie, Timothy Beukelman, Nicholas P McCormick, Jeffrey R Curtis   +3 more
wiley   +1 more source

Predicting blunt cerebrovascular injury in pediatric trauma: Validation of the Utah Score [PDF]

, 2017
Risk factors for blunt cerebrovascular injury (BCVI) may differ between children and adults, suggesting that children at low risk for BCVI after trauma receive unnecessary computed tomography angiography (CTA) and high-dose radiation.
Akbari, Hassan, Birkas, Yekaterina, Bollo, Robert J, Gannon, Stephen, Jea, Andrew, Kestle, John R, Limbrick, David D, Jr, Naftel, Robert P, Prather, Colin T, Ravindra, Vijay M, Riva-Cambrin, Jay, Shannon, Chevis, Sivakumar, Walavan, Yang, George L   +13 more
core   +2 more sources

Spinal diffuse midline glioma: An unusual case presentation

South African Journal of Oncology
Primary spinal cord neoplasms are rare, accounting for 1% of paediatric central nervous system tumours. The majority of which are low-grade gliomas (LGG). A teenage male presented with rapidly progressive lower limb paralysis. He subsequently underwent a
Nadia Beringer, Kate G. Bennett, Despina Demopoulos, Marelize Reynders, Linda Doedens, Felicia Tshite, Deborah Pearce, Raazik Gani, Dawn-Lee van der Byl, Duvern Ramiah, Pieter E. Boshoff, Christos Profyris, John Ouma, Abhijit Joshi, Simon Bailey   +14 more
doaj   +1 more source

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

Advanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

Advanced Healthcare Materials, EarlyView.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans, Anna P. Constantinou, Matthew J. Kibble, Valeria Nele, Daniel Reumann, Luca Bau, Sebastien J. P. Callens, James P. K. Armstrong, Nicolas Newell, Constantin C. Coussios, Molly M. Stevens, Michael D. Gray   +11 more
wiley   +1 more source

Bioprinting Organs—Science or Fiction?—A Review From Students to Students

Advanced Healthcare Materials, EarlyView.
Bioprinting artificial organs has the potential to revolutionize the medical field. This is a comprehensive review of the bioprinting workflow delving into the latest advancements in bioinks, materials and bioprinting techniques, exploring the critical stages of tissue maturation and functionality.
Nicoletta Murenu, Camilla Mussoni, Mateo S. Andrade Mier, Paula Buettner, Nathaly Chicaiza‐Cabezas, Yi‐Yu Robin Dai, Jessica Faber, Maren Fiedler, Zan Lamberger, Xuen Jen Ng, Vanessa Moessler, Anna Rederer, Jonas Roeder, Sabrina Stecher, Katinka Theis, Jeanette Weigelt, Silvia Budday, Gregor Lang, Natascha Schaefer   +18 more
wiley   +1 more source

Clinical Use of S53P4 Bioactive Glass in the Treatment of Bone Defects and Infected Bone: A Systematic Review of the Quality of Clinical Outcomes and A Grade Assessment

Advanced Healthcare Materials, EarlyView.
Bioactive glass (BAG) S53P4 is a synthetic bone substitute. Clinically it has been used in the treatment of benign bone tumor surgery, in spine surgery, in trauma surgery, in frontal sinus surgery, in diabetic foot osteomyelitis surgery, in mastoid surgery, in oral and maxillofacial surgery in more than 4000 patients, with excellent clinical long‐term ...
Sebastian CE Lindfors, Chris JJ Arts, Nina C Lindfors   +2 more
wiley   +1 more source

Low-grade dorsal spinal cord astrocytoma presented with paraplegia following minor trauma

Saudi Journal of Medicine and Medical Sciences, 2014
Although they constitute about one third of spinal cord glial neoplasms, low-grade astrocytomas can present variably. Post-traumatic neurologic dysfunction due to low-grade spinal cord gliomas is an uncommon event. The authors report a case of paraplegia
Bander F Al-Dhafery, Abdullah S Al-Mulhim, Hossain A. A. Alola   +2 more
doaj   +1 more source

Body Biofluids for Minimally‐Invasive Diagnostics: Insights, Challenges, Emerging Technologies, and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao, Chandan Kumar Mandal, Fernando Patolsky   +2 more
wiley   +1 more source

Preoperative spinal tumor embolization: an institutional experience with Onyx. [PDF]

, 2013
BACKGROUND: Preoperative embolization has the potential to decrease intraoperative blood loss and facilitate spinal cord decompression and tumor resection.
Ashour, Berkefeld, Bilsky, Chalouhi, Choi, David Hasan, Deshmukh, Elhammady, Elhammady, George M. Ghobrial, Gore, Guzman, James Harrop, Kato, Kickuth, Kobayashi, L. Fernando Gonzalez, Manke, Nohra Chalouhi, Olerud, O’Reilly, Pascal Jabbour, Prabhu, Rehak, Richard T. Dalyai, Robert H. Rosenwasser, Robial, Shi, Smith, Stavropoula Tjoumakaris, Taniguchi, Trubenbach, Vetter   +32 more
core   +2 more sources