Results 171 to 180 of about 903,662 (366)

Biodegradable Medical Implants: Reshaping Future Medical Practice

open access: yesAdvanced Science, EarlyView.
Biodegradable medical implants are transforming future healthcare by providing sustainable, biocompatible solutions that eliminate secondary removal procedures, enhancing patients’ physical and psychological comfort, and reducing economic burdens.
Bo Xia   +4 more
wiley   +1 more source

Polyphenol‐Based Functional Materials: Structural Insights, Composite Strategies, and Biomedical Applications

open access: yesAdvanced Science, EarlyView.
This schematic representation illustrates the interaction mechanisms between polyphenolic compounds and various materials (metals, proteins, polysaccharides, alkaloids, etc.). And explains the potential clinical application value of these materials (nanoparticles, coatings, films, capsules, and hydrogels constructed using polyphenols) in the fields of ...
Songwen Xue   +6 more
wiley   +1 more source

Mixed Lineage Kinase Domain‐Like Protein (MLKL): From Mechanisms to Therapeutic Opportunities

open access: yesAdvanced Science, EarlyView.
The mixed lineage kinase domain‐like protein (MLKL) acts as the executioner in the necroptosis pathway, transitioning from an inactive to active state through phosphorylation, oligomerization, membrane recruitment, and membrane insertion, ultimately forming membrane hotpots.
Lijuan Xu, Chunlin Zhuang
wiley   +1 more source

Epithelioid neoplasm of the spinal cord in a child with spinal muscular atrophy treated with onasemnogene abeparvovec [PDF]

open access: hybrid, 2023
Laura Retson   +10 more
openalex   +1 more source

Neurophilic Biomimetic Lipoprotein‐Mediated Targeted Nerve Growth Factor Delivery for Traumatic Brain Injury Therapy

open access: yesAdvanced Science, EarlyView.
Design of neurophilic biomimetic lipoprotein for intracerebral delivery of nerve growth factor (NGF) to traumatic brain injury (TBI). Nc‐rHDL@P can cross the BBB through ApoE3‐receptors interaction and target neurons via αRDP‐nAChR interaction. Nc‐rHDL@P delivers NGF to the lesion sites, rescues neurons, curbs inflammation, boosts sensorimotor and ...
Jialin Huang   +21 more
wiley   +1 more source

Near‐Infrared‐Responsive Digital PCR‐Assisted Renal Cancer Exosomal miRNAs Insights and Regulation of Macrophage Polarization

open access: yesAdvanced Science, EarlyView.
A near‐infrared‐responsive digital Polymerase Chain Reaction technique with triple‐color coding profiles renal cancer exosomal microRNA biomarkers and their impact on macrophage polarization. Engineered miR‐34‐loaded exosomes via electroporation saturate molecular sponges, downregulating STAT3 in recipient macrophages to prolong M2 polarization. Stable
Lexiang Zhang   +11 more
wiley   +1 more source

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