Results 61 to 70 of about 903,662 (366)

Biological and Clinical Aspects of Metastatic Spinal Tumors

Cancers, 2022
Simple Summary Spine metastases are a common life-threatening complication of advanced-stage malignancies and often result in poor prognosis. Symptomatic spine metastases develop in the course of about 10% of malignant neoplasms.
J. Litak, Wojciech Czyżewski, Michał Szymoniuk, Leon Sakwa, B. Pasierb, Joanna Litak, Zofia Hoffman, P. Kamieniak, J. Roliński   +8 more
semanticscholar   +1 more source

ACSS2 involved in acetyl‐CoA synthesis regulates skeletal muscle function

FEBS Letters, EarlyView.
The enzyme acyl‐coenzyme A synthetase short‐chain family member‐2 (ACSS2) catalyzes the conversion of acetate to acetyl‐CoA, but its function in skeletal muscle is unclear. We studied ACSS2 deficiency in mouse and fly models. Skeletal muscle from the mouse model showed atrophic fibers, excess lipid, and depleted NADH.
Mekala Gunasekaran, Gloriana Campos, Natalya M. Wells, Khanhlinh Lambuu, Isabelle Draper, Christina A. Pacak, Peter B. Kang   +6 more
wiley   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

THE SINS SCALE IN THE EVALUATION OF STABILITY IN PATIENTS WITH SPINAL METASTASIS

Coluna/Columna
Objective To evaluate the distribution of patients seen in the emergency care unit of the Instituto do Câncer do Estado de São Paulo in the categories “stable”, “indeterminate” and “unstable” as classified by the SINS scale. Methods The medical charts
ARIEL FALBEL LUGÃO, CLOVIS CASTANHO SILVEIRA JUNIOR, WILLIAM GEMIO JACOBSEN TEIXEIRA, ALEXANDRE FOGAÇA CRISTANTE   +3 more
doaj   +1 more source

Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features [PDF]

, 2018
Diffuse leptomeningeal glioneuronal tumors (DLGNT) represent rare CNS neoplasms which have been included in the 2016 update of the WHO classification. The wide spectrum of histopathological and radiological features can make this enigmatic tumor entity ...
Brandner, Sebastian, Brück, Wolfgang, Capper, David, Chiang, Jason, Cruz Martinez, Ofelia, Deng, Maximilian Y., Ebinger, Martin, Ellison, David W., Giangaspero, Felice, Gärtner, Jutta, Hansford, Jordan R., Hartmann, Christian, Hernáiz-Driever, Pablo, Jaunmuktane, Zane, Jones, David T. W., Korshunov, Andrey, Leipold, Alfred, Milde, Till, Monoranu, Camelia-Maria, Mora, Jaume, Morales la Madrid, Andres, Nozza, Paolo, Paulus, Werner, Pfister, Stefan M., Pietsch, Torsten, Rüdiger, Thomas, Sahm, Felix, Schittenhelm, Jens, Schuhmann, Martin U., Sill, Martin, Sommer, Clemens, Stoler, Iris, Tietze, Anna, von Deimling, Andreas, Wittmann, Andrea   +34 more
core   +1 more source

Recent advances and new discoveries in the pipeline of the treatment of primary spinal tumors and spinal metastases: A scoping review.

Neuro-Oncology, 2021
The field of spinal oncology has substantially evolved over the past decades. This review synthesizes and appraises what was learned and what will potentially be discovered from the recently completed and ongoing clinical studies related to the treatment
J. Furlan, Jefferson R. Wilson, E. Massicotte, A. Sahgal, Fehlings Michael   +4 more
semanticscholar   +1 more source

Diagnostic Challenge: The Case of a 70‐Year‐Old Man Who Presents With Progressive Vision Loss and Headaches

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 70‐year‐old presents with 6 weeks of progressive bilateral vision loss and headaches. He was also recently treated for presumed sciatica. His exam on admission is notable for poor visual acuity (no light perception), optic nerve atrophy bilaterally with swelling and disc hemorrhage on the left eye and left foot drop.
Malya Sahu, Rohini Samudralwar
wiley   +1 more source

Spinal cysticercosis: A case report

Radiology Case Reports, 2023
Spinal cysticercosis is a rare and severe cysticercosis complication. The pathology is from the inflammatory reaction and granuloma formation around the eggs, which cause focal neurological deficits. Because of the rarity of this condition, diagnosis may
Bui Huy Manh, MD, Tran Dat, MD, Vu Trung Hai, MD, Dong-Van He, MD, Duong Dai Ha, MD, Nguyen-Van Que, MD, Nguyen Minh Duc, MD   +6 more
doaj   +1 more source

Relevance of Kappa and Lambda Free Light Chains in Autoimmune Astrocytopathy Associated With Anti‐GFAP Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction The kappa‐free light chain (κ‐FLC) index is known to be highly sensitive and specific for diagnosing multiple sclerosis (MS), while little is understood about lambda (λ)‐FLC. This study assessed the κ‐FLC and λ‐FLC indices in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.
Michael Levraut, Romain Marignier, Mikael Cohen, Jeanne Benoit, Cassandre Landes‐Chateau, Elisabeth Maillart, Marion Cremoni, Barbara Seitz‐Polski, Anne‐Laurie Pinto, Pauline Dumez, Jérôme Honnorat, Christine Lebrun‐Frenay   +11 more
wiley   +1 more source

Rare Cause of Back Pain in a Paediatric Patient with Aneurysmal Bone Cyst: An Illustrative Case

Çocuk Dergisi
Spinal tumors are rare in the pediatric age. The most common symptoms of spinal tumors are neck, back, and waist pain. Diagnosis is often delayed in patients presenting with nonspecific symptoms (e.g. pain).
Aynur Kaya Karaca, Büşra Zeynep Yılmaz, Ahmet Osman Kılıç, Ganime Dilek Emlik, Mehmet Fatih Erdi   +4 more
doaj   +1 more source