Results 11 to 20 of about 1,329 (129)
Case Reports in Orthopedics, 2020 Spondylosis deformans is a type of spinal claw osteophytosis which can be found on the anterolateral vertebral bodies of any region, and which consists of protrusions of intervertebral disc tissue covered by a bony shell.
Amy H. Amabile +6 more
doaj +2 more sources
Degenerative Thoracic Myelopathy: A Scoping Review of Epidemiology, Genetics, and Pathogenesis [PDF]
Global Spine Journal, 2023 Study Design Literature Review. Objective Myelopathy affecting the thoracic spinal cord can arise secondary to several aetiologies which have similar presentation and management.
Tanzil Rujeedawa BA +14 more
doaj +4 more sources
The distribution, determinants, and clinical correlates of vertebral osteophytosis: A population based survey [PDF]
, 1999 Objective. Vertebral osteophytes are a characteristic feature of intervertebral disc degeneration. There are, however, few population data concerning the occurrence of and clinico-biological correlates of vertebral osteophytes in both the dorsal and ...
O'Neill, Terence W. +8 more
core +4 more sources
Two cases of skeletal fluorosis from the historic cemetery at Zhangwan, Henan Province, China
International Journal of Osteoarchaeology, Volume 33, Issue 6, Page 1052-1063, November/December 2023., 2023 Abstract Skeletal fluorosis is a systemic chronic disease caused by long‐term intake of excessive fluoride, which accumulates in bone tissue and causes changes to the bone and periosteal tissue. Skeletal fluorosis is rarely considered in paleopathological analyses, but in areas with relatively high fluoride in the environment, it may be an important ...
Yawei Zhou +3 more
wiley +1 more source
An update on mobility assessment of dogs with musculoskeletal disease
Journal of Small Animal Practice, Volume 64, Issue 10, Page 599-610, October 2023., 2023 Mobility impairments associated with musculoskeletal diseases, such as osteoarthritis and degenerative joint disease, affect approximately 200,000 dogs annually and pose a notable challenge to canine health and welfare. Osteoarthritis causes the remodelling of synovial joints, alongside inflammation and impaired mechanical function which can be ...
N. Clark, E. Comerford
wiley +1 more source
Arthritis &Rheumatology, Volume 75, Issue 7, Page 1139-1151, July 2023., 2023 Objective Many patients with acromegaly, a hormonal disorder with excessive growth hormone (GH) production, report pain in joints. We undertook this study to characterize the joint pathology of mice with overexpression of bovine GH (bGH) or a GH receptor antagonist (GHa) and to investigate the effect of GH on regulation of chondrocyte cellular ...
Shouan Zhu +13 more
wiley +1 more source
A novel meningioma with tyrosine‐rich crystals in a 6‐year‐old Great Dane
Journal of Veterinary Internal Medicine, Volume 37, Issue 4, Page 1501-1506, July/August 2023., 2023 Abstract A 6‐year‐old female spayed Great Dane was evaluated for acute onset cluster seizures. Magnetic resonance imaging (MRI) identified a mass in the olfactory bulbs with a large mucoid component caudal to the primary mass. The mass was removed via transfrontal craniotomy and histopathology revealed a tyrosine crystalline‐rich, fibrous meningioma ...
Kara Majors +5 more
wiley +1 more source
Rare and Common Variants in GALNT3 May Affect Bone Mass Independently of Phosphate Metabolism
Journal of Bone and Mineral Research, Volume 38, Issue 5, Page 678-691, May 2023., 2023 ABSTRACT Anabolic treatment options for osteoporosis remain limited. One approach to discovering novel anabolic drug targets is to identify genetic causes of extreme high bone mass (HBM). We investigated a pedigree with unexplained HBM within the UK HBM study, a national cohort of probands with HBM and their relatives. Whole exome sequencing (WES) in a
Neelam Hassan +15 more
wiley +1 more source
Intervertebral disc degeneration and how it leads to low back pain
JOR SPINE, Volume 6, Issue 1, March 2023., 2023 Data generated by animal models over the last decade has made invaluable contributions to the identification of molecular events occurring in and contributing to intervertebral disc (IVD) degeneration and pain generation and has identified several potential therapeutic targets.
Ashish D. Diwan, James Melrose
wiley +1 more source
Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis [PDF]
, 2013 Introduction: The objective was to investigate potential gene-environment interaction between body mass index (BMI) and each of eight TGFβ1 polymorphisms in knee and hip osteoarthritis (OA).
Muthuri, Stella G. +19 more
core +1 more source