Results 11 to 20 of about 288,613 (130)

A Biometrical investigation into the relationship between vertebral joint osteophytosis and body proportion biomechanics. [PDF]

Occupational loading is a significant risk factor for back pain and vertebral joint disease. Although biomechanical principles predict that spinal loading is affected by body proportion, particularly with differences in upper to lower body measurements ...
Pamplin, Gary David
core   +9 more sources

Arthroscopic Centralization During Meniscal Allograft Transplantation. [PDF]

Arthrosc Tech
Abstract Pathologic extrusion of the meniscus, defined as displacement of more than 3 mm beyond the tibial plateau border, can disrupt tibiofemoral contact mechanics by reducing hoop strain resistance and increasing articular cartilage contact pressure.
Dhanjani S, Wang T.
europepmc   +2 more sources

MRI‐based synthetic CT in the detection of knee osteoarthritis: Comparison with CT

Journal of Orthopaedic Research, Volume 41, Issue 11, Page 2530-2539, November 2023., 2023
Abstract Magnetic resonance Imaging is the gold standard for assessment of soft tissues; however, X‐ray‐based techniques are required for evaluating bone‐related pathologies. This study evaluated the performance of synthetic computed tomography (sCT), a novel MRI‐based bone visualization technique, compared with CT, for the scoring of knee ...
Saeed Arbabi, Wouter Foppen, Willem Paul Gielis, Marijn van Stralen, Mylène Jansen, Vahid Arbabi, Pim A. de Jong, Harrie Weinans, Peter Seevinck   +8 more
wiley   +1 more source

Two cases of skeletal fluorosis from the historic cemetery at Zhangwan, Henan Province, China

International Journal of Osteoarchaeology, Volume 33, Issue 6, Page 1052-1063, November/December 2023., 2023
Abstract Skeletal fluorosis is a systemic chronic disease caused by long‐term intake of excessive fluoride, which accumulates in bone tissue and causes changes to the bone and periosteal tissue. Skeletal fluorosis is rarely considered in paleopathological analyses, but in areas with relatively high fluoride in the environment, it may be an important ...
Yawei Zhou, Kailu Liu, Fei Yan, Elizabeth Berger   +3 more
wiley   +1 more source

An update on mobility assessment of dogs with musculoskeletal disease

Journal of Small Animal Practice, Volume 64, Issue 10, Page 599-610, October 2023., 2023
Mobility impairments associated with musculoskeletal diseases, such as osteoarthritis and degenerative joint disease, affect approximately 200,000 dogs annually and pose a notable challenge to canine health and welfare. Osteoarthritis causes the remodelling of synovial joints, alongside inflammation and impaired mechanical function which can be ...
N. Clark, E. Comerford
wiley   +1 more source

Promotion of Joint Degeneration and Chondrocyte Metabolic Dysfunction by Excessive Growth Hormone in Mice

Arthritis &Rheumatology, Volume 75, Issue 7, Page 1139-1151, July 2023., 2023
Objective Many patients with acromegaly, a hormonal disorder with excessive growth hormone (GH) production, report pain in joints. We undertook this study to characterize the joint pathology of mice with overexpression of bovine GH (bGH) or a GH receptor antagonist (GHa) and to investigate the effect of GH on regulation of chondrocyte cellular ...
Shouan Zhu, Huanhuan Liu, Trent Davis, Craig R. G. Willis, Reetobrata Basu, Luke Witzigreuter, Stephen Bell, Nathaniel Szewczyk, Martin K. Lotz, Marcheta Hill, Roberto J. Fajardo, Patrick M. O'Connor, Darlene E. Berryman, John J. Kopchick   +13 more
wiley   +1 more source

Radiographic Assessment of Spinal Degeneration in Vervet Monkeys (Chlorocebus aethiops): Prevalence, Patterns, and Relevance to Primate Aging Models. [PDF]

Am J Primatol
Radiographic evaluation of 70 vervet monkeys (Chlorocebus aethiops) maintained under human care revealed a high prevalence of age‐related spinal degeneration. Osteophytes emerged earliest and most prominently in the lumbar region. These region‐specific patterns parallel those reported in other catarrhine primates, supporting C.
Portal CGR, Imbeloni AA, Rahal SC, da Silva WB, Kano WT, Yamashita S, Mayor P, Monteiro FOB.   +7 more
europepmc   +2 more sources

A novel meningioma with tyrosine‐rich crystals in a 6‐year‐old Great Dane

Journal of Veterinary Internal Medicine, Volume 37, Issue 4, Page 1501-1506, July/August 2023., 2023
Abstract A 6‐year‐old female spayed Great Dane was evaluated for acute onset cluster seizures. Magnetic resonance imaging (MRI) identified a mass in the olfactory bulbs with a large mucoid component caudal to the primary mass. The mass was removed via transfrontal craniotomy and histopathology revealed a tyrosine crystalline‐rich, fibrous meningioma ...
Kara Majors, Savannah M. Rocha, Rebecca Windsor, Ronald B. Tjalkens, Julia Engelien, Tawfik Aboellail   +5 more
wiley   +1 more source

Rare and Common Variants in GALNT3 May Affect Bone Mass Independently of Phosphate Metabolism

Journal of Bone and Mineral Research, Volume 38, Issue 5, Page 678-691, May 2023., 2023
ABSTRACT Anabolic treatment options for osteoporosis remain limited. One approach to discovering novel anabolic drug targets is to identify genetic causes of extreme high bone mass (HBM). We investigated a pedigree with unexplained HBM within the UK HBM study, a national cohort of probands with HBM and their relatives. Whole exome sequencing (WES) in a
Neelam Hassan, Celia L. Gregson, Haotian Tang, Marc van der Kamp, Paul Leo, Aideen M. McInerney‐Leo, Jie Zheng, Maria Luisa Brandi, Jonathan C. Y. Tang, William Fraser, Michael D. Stone, Elin Grundberg, Anglo‐Australasian Genetics Consortium, Matthew A. Brown, Emma L. Duncan, Jonathan H. Tobias   +15 more
wiley   +1 more source

Intervertebral disc degeneration and how it leads to low back pain

JOR SPINE, Volume 6, Issue 1, March 2023., 2023
Data generated by animal models over the last decade has made invaluable contributions to the identification of molecular events occurring in and contributing to intervertebral disc (IVD) degeneration and pain generation and has identified several potential therapeutic targets.
Ashish D. Diwan, James Melrose
wiley   +1 more source