Results 251 to 260 of about 912,627 (390)

Age and Spinal Level as Predictors of Lumbar Disc Degeneration in Humans and Mice: A Comparative Analysis

JOR SPINE, Volume 8, Issue 4, December 2025.
Mouse models are commonly used to study IVD degeneration and related neurological conditions that especially impact elder population. However, how well mice replicate human pathology remains unclear. This study compared lumbar IVD degeneration patterns across age and spinal levels in humans and mice.
Ravij Mehta, Sarthak Mohanty, Andrew Parker Hallmark, Veeraj Shah, Tom Ross, Eric A. Bogner, Tejbir S. Pannu, Mathieu Bannwarth, Sohrab Virk, Sravisht Iyer, James C. Farmer, Russel C. Huang, Darren R. Lebl, Bernard A. Rawlins, Harvinder S. Sandhu, Han Jo Kim, Matthew E. Cunningham, Sheeraz Qureshi, Todd J. Albert, Chitra L. Dahia   +19 more
wiley   +1 more source

Temporary Relative Lumbar Spinal Stenosis After Skip Partial Laminectomies in an Elderly Woman: A Case Report. [PDF]

Cureus
Kinoshita H, Hongo M, Matsuura H, Takeshima M, Miyakoshi N.   +4 more
europepmc   +1 more source

Lactate Metabolism in Intervertebral Disc Degeneration: Unveiling Novel Mechanisms Through Bioinformatics

JOR SPINE, Volume 8, Issue 4, December 2025.
This graphical abstract outlines the workflow to uncovering lactate metabolism‐related mechanisms in intervertebral disc degeneration (IDD). First, three IDD datasets (GSE34095: 3 IDD vs 3 control; GSE147383: 2 IDD vs 2 control; GSE70362: 16 IDD vs 8 control) were sourced from the Gene Expression Omnibus (GEO) database, and 73 lactate metabolism ...
Haiyan Sun, Mingwei He, Jinlei Pang, Xiangfei Guo, Yansong Huo, Jun Ma   +5 more
wiley   +1 more source

Correlation between the severity of lumbar spinal stenosis and lumbar paraspinal muscle atrophy. [PDF]

Am J Transl Res
Mu X, Zhao C, Shan Z, Deng L, Zhou X, Li L.   +5 more
europepmc   +1 more source

Therapeutic Approaches for Enhancing Spinal Fusion in Low Back Pain: A Review With a Focus on the Elderly

JOR SPINE, Volume 8, Issue 4, December 2025.
The review summarizes the current clinical problems of non‐spinal fusions in orthopaedics. I refers to selected biological examples of how ossification can be better achieved in elderly patients. ABSTRACT Background Low back pain (LBP) is a prevalent cause of disability worldwide, particularly among the elderly, with degenerative spinal conditions ...
Shuimu Chen, Zhen Li, Sebastian F. Bigdon, Sonja Häckel, Christoph E. Albers, Benjamin Gantenbein   +5 more
wiley   +1 more source

Modified Frailty Index-11-A New Predictor of Postoperative Complications in the Aging Thoracic Spinal Stenosis Patients. [PDF]

Orthop Surg
Xu Z, Hu Y, Yuan L, Chen G, Jiang S, Guo X, Jiang Y, Zhong W, Li W, Chen Z, Sun C.   +10 more
europepmc   +1 more source

Profile of Lumbar Spinal Canal Stenosis at Prof. Dr. I.G.N.G Ngoerah Central General Hospital from Period of January 2021-December 2022

Trifena Lisanaias, I Ketut Suyasa, Anak Agung Gde Yuda Asmara   +2 more
openalex   +1 more source

Using a percutaneous spinal endoscopy unilateral posterior interlaminar approach to perform bilateral decompression for patients with lumbar lateral recess stenosis

, 2019
Zhijun Xin, Peng Huang, Guoquan Zheng, Wenbo Liao, Xifeng Zhang, Yan Wang   +5 more
openalex   +1 more source

Unilateral spinal motion segment rotational deformity causing foraminal stenosis

, 2020
Fitz-Gerald Connor, Niels Hammer, Kieser David   +2 more
openalex   +1 more source

Unveiling the Potential Mechanism of Asymmetric Fat Infiltration in Paraspinal Muscles of Adult Degenerative Scoliosis: The Role of the Hsa_circ_0006156/miR‐122‐5p/PPARA Regulatory Network

JOR SPINE, Volume 8, Issue 4, December 2025.
Mechanism of ADS Paraspinal Muscle Fatty Infiltration. ABSTRACT Background Paraspinal muscle degeneration, particularly fat infiltration, is a prominent feature of adult degenerative scoliosis (ADS), which impairs spinal stability, accelerates disease progression, and contributes to poor clinical outcomes.
Xueneng Yang, Limin Guo, Jun Shu
wiley   +1 more source