Results 251 to 260 of about 87,347 (355)

Wharton's Jelly Mesenchymal Stromal Cell‐Derived Extracellular Vesicles Attenuate Intervertebral Disc Degeneration Under Inflammatory Stress in an In Vitro 3D Culture System

open access: yesJOR SPINE, Volume 8, Issue 3, September 2025.
This study explores the therapeutic potential of extracellular vesicles (EVs) derived from Wharton's Jelly mesenchymal stem cells in an in vitro 3D model of intervertebral disc degeneration under inflammatory stress. The treatment with WJ‐MSC‐EVs enhanced nucleus pulposus cell proliferation, viability, and extracellular matrix synthesis while reducing ...
Veronica Tilotta   +8 more
wiley   +1 more source

Comprehensive Evaluation of Facet Joints Osteoarthritis Radiological Features on Lumbar CT: A Multitask Deep Learning Approach

open access: yesJOR SPINE, Volume 8, Issue 3, September 2025.
To develop a multitask deep learning (DL) model for assessing the severity of five radiological features of facet joint osteoarthritis (FJOA) on lumbar spine CT and evaluate the performance of readers with DL assistance. ABSTRACT Background Accurately evaluating the radiological features of facet joint osteoarthritis (FJOA) may help to elucidate its ...
Yunfei Wang   +12 more
wiley   +1 more source

Comparison of twelve‐layer concentric object (TLCO) and Line segmentations methods to determine the renal corticomedullary sodium gradient (CMSG) with a 3 T MRI

open access: yesMagnetic Resonance in Medicine, Volume 94, Issue 3, Page 1318-1325, September 2025.
Abstract Purpose 23Na MRI is a functional imaging technique that facilitates measurements of the renal corticomedullary sodium gradient (CMSG). The CMSG can be determined by a region of interest (ROI) in the renal parenchyma along the corticomedullary axis (Line method) or by dividing the renal parenchyma into concentric layers, using the twelve‐layer ...
Patrik Jan Gallinnis   +11 more
wiley   +1 more source

Sleep Quality in Chronic Pain Patients With and Without Strong Opioid Use: An Observational Study Using a Wearable Device

open access: yesNeuropsychopharmacology Reports, Volume 45, Issue 3, September 2025.
Low‐dose strong opioids improved sleep efficiency in chronic pain patients, whereas high doses (≥ 60 mg MEDD) impaired sleep. Wearable device and self‐report data highlight the need for careful opioid titration and sleep monitoring to balance analgesia with preservation of sleep quality.
Hiroko Ikemiya   +7 more
wiley   +1 more source

Ten-Year Clinical Outcomes After Decompression Surgery for Lumbar Spinal Stenosis: The Impact of Preoperative Modic Changes. [PDF]

open access: yesGlobal Spine J
Watanabe K   +11 more
europepmc   +1 more source

Depression is associated with poorer outcome of lumbar spinal stenosis surgery

open access: green, 2007
Sanna Sinikallio   +7 more
openalex   +2 more sources

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