Results 71 to 80 of about 87,347 (355)

A new staging system for hereditary transthyretin amyloidosis in the era of specific amyloidosis therapies

ESC Heart Failure, EarlyView.
The aim of our study was to develop a more accurate staging system for hereditary ATTR patients currently receiving specific treatment. A staging system was created using as criteria: GLS ≤ −11%, NT‐proBNP ≤ 2,000 ng/L, and eGFR ≤ 65 mL/min. We managed to accurately stratify patients into three disease stages, significantly different in terms of ...
Gabriela Neculae, Amira Zaroui, Robert Adam, Mounira Kharoubi, Benoit Funalot, Daniel Coriu, Ruxandra Jurcut, Thibaud Damy   +7 more
wiley   +1 more source

Focusing on spinal stenosis: emerging discoveries concerning Alendronate-induced risks and genetic drug targets

Journal of Orthopaedic Surgery and Research
Background Spinal stenosis is a common disease in clinical practice, and drug use is one of its potential predisposing factors. Alendronate, a widely used clinical drug for osteoporosis treatment, has the potential to trigger spinal stenosis.
Nan Yang, Jingkai Di, Xiang Han, Wei Zhang, Xinliang Cui, Haoyu Feng   +5 more
doaj   +1 more source

Cardiac interventions in patients with achondroplasia: a systematic review. [PDF]

, 2020
Patients with achondroplasia and other causes of dwarfism suffer from increased rates of cardiovascular disease relative to the remainder of the population.
Choi, Jae Hwan, Gordon, Jonathan S, Maynes, Elizabeth J, O\u27Malley, Thomas J, Phan, Kevin, Sukhavasi, Amrita, Tchantchaleishvili, Vakhtang   +6 more
core   +1 more source

Research progress of neurovascular units involved in ischemic stroke

Ibrain, EarlyView.
The brain receives less blood when an ischemic stroke develops, which damages neurons and leads to an increased release of Pro‐inflammatory mediators that activate neurovascular unit (NVU). When the tight junctions are broken and the basement membrane is disrupted by matrix metalloproteinases produced by active endothelial and pericellular cells ...
Yu Yang, Hao Tong, Zhuo‐Fan Ye, Zu‐Cai Xu, Tao Tao   +4 more
wiley   +1 more source

Unveiling therapeutic targets for spinal stenosis from genetic insights: a Mendelian randomization analysis

Scientific Reports
Spinal stenosis is a commonly chronic spinal degenerative disease, which is a major cause of pain and dysfunction in the elderly. Mendelian randomization (MR) has been widely applied to repurpose licensed drugs and identify novel therapeutic targets ...
Zhaopeng Fan, Bohong Chen, Le Ding, Hua Guo   +3 more
doaj   +1 more source

Lumbar Stenosis: A Recent Update by Review of Literature [PDF]

Asian Spine Journal, 2015
Degeneration of the intervertebral disc results in initial relative instability, hypermobility, and hypertrophy of the facet joints, particularly at the superior articular process.
Seung Yeop Lee, Tae-Hwan Kim, Jae Keun Oh, Seung Jin Lee, Moon Soo Park   +4 more
doaj   +1 more source

Simultaneous Visualization of the Carotid and Subclavian Arteries Using Non–Contrast‐Enhanced MR Angiography With a 3D Fast Field Echo Sequence and Time‐Spatial Labeling Inversion Pulse: A Comparison With 3D Time‐of‐Flight MR Angiography

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Carotid artery stenosis is a major cause of stroke. Non‐contrast MR angiography (MRA) using time‐spatial labeling inversion pulse (Time‐SLIP) may offer potential advantages over 3D time‐of‐flight (TOF)‐MRA for simultaneous visualization of carotid, vertebral, and subclavian arteries, but remains uninvestigated.
Hitomi Numamoto, Koji Fujimoto, Sachi Okuchi, Kanae K. Miyake, Yasutaka Fushimi, Takakuni Maki, Yuichiro Monzen, Rimika Imai, Nobuyasu Ichinose, Yuji Nakamoto   +9 more
wiley   +1 more source

Atlantoaxial dislocation in an adolescent with juvenile spondyloarthritis

Хирургия позвоночника, 2019
Atlantoaxial dislocation with spinal canal stenosis not associated with craniovertebral junction malformations and traumatic injury is a rare pathology in children and adolescents. A clinical case of the diagnosis and surgical treatment of atlantoaxial
Sergei V. Vissarionov, Vadim A. Manukovskiy, Vladislav V. Murashko   +2 more
doaj   +1 more source

Lumbar interspinous process fixation and fusion with stand-alone interlaminar lumbar instrumented fusion implant in patients with degenerative spondylolisthesis undergoing decompression for spinal stenosis [PDF]

, 2016
STUDY DESIGN: Prospective cohort study. PURPOSE: To assess the ability of a stand-alone lumbar interspinous implant (interspinous/interlaminar lumbar instrumented fusion, ILIF) associated with bone grafting to promote posterior spine fusion in ...
Cinotti, Gianluca, Menchetti, Pier Paolo Maria, Paolino, Michela, Postacchini, Franco, Postacchini, Roberto, Sessa, Pasquale   +5 more
core   +2 more sources

Combining Detailed Fetal Anatomy Scanning in the NT Window Versus Early Second Trimester Scanning at 14–16 Weeks

Journal of Ultrasound in Medicine, EarlyView.
Objectives First‐trimester ultrasound has evolved to incorporate a detailed fetal anatomy scan (FAS) with nuchal translucency (NT) screening. Many institutions use a 2‐visit protocol: NT followed by detailed FAS at 14–16 weeks. We aimed to evaluate whether integrating detailed FAS into the NT window (12 + 5 to 13 + 6 weeks) is non‐inferior in ...
Tomer Shwartz, Sarah M. Cohen, Michal Lipschuetz, Hila Hochler, Yaron Zalel, Dan V. Valsky, Simcha Yagel   +6 more
wiley   +1 more source