Results 1 to 10 of about 6,643 (88)

Pathogenesis of Spinal Subdural Hematoma Based on Histopathological Findings: A Case Report [PDF]

open access: yesNMC Case Report Journal
Toshihiro Takami   +2 more
exaly   +2 more sources

Recognizing Signs of Abusive Head Trauma

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Background Abusive head trauma (AHT) remains the leading cause of fatal traumatic brain injury in infants and young children. Diagnosis is frequently delayed or missed due to nonspecific clinical presentation and unreliable histories, making neuroimaging a critical component of the diagnostic process. Objective This review synthesises computed
Maísa Naomi Irie   +7 more
wiley   +1 more source

De Novo 2.2 Mb 19q13.42–q13.43 Microdeletion Encompassing U2AF2: Support for a Haploinsufficiency Model

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2350-2356, October 2026.
ABSTRACT U2 small nuclear RNA auxiliary factor 2 (U2AF2) is an essential pre‐mRNA splicing factor involved in the early stages of pre‐mRNA splicing. To date, multiple individuals have been reported with predominantly heterozygous missense variants presenting intellectual disability, speech and motor delays, seizures, hypotonia, and thin or hypoplastic ...
Amanda Toledo   +3 more
wiley   +1 more source

Comorbidities and health‐care use prior to early‐onset Alzheimer's disease: A population‐based case–control study

open access: yesAlzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION We examined whether comorbidities and health‐care use differ between individuals later diagnosed with early‐onset Alzheimer's disease (EOAD) and matched controls during the 15 years preceding diagnosis. METHODS This population‐based case–control study included 407 EOAD patients diagnosed at two Finnish university hospitals (2010 ...
Laura Leppänen   +13 more
wiley   +1 more source

Safety of Nonsteroidal Anti‐Inflammatory Drug Use in Traumatic Brain Injury

open access: yesPharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 10, October 2026.
ABSTRACT Background Use of nonsteroidal anti‐inflammatory drugs (NSAIDs) after a traumatic brain injury (TBI) is controversial due to potential worsening of an intracranial hemorrhage (ICH). This study evaluated if NSAID use within 14 days of TBI was associated with a clinically significant progression of intracranial bleed (PIB).
Jennifer Beavers   +10 more
wiley   +1 more source

Cost‐Effectiveness of Decompressive Craniectomy in Severe Traumatic Brain Injury Patients: A Systematic Review of Economic Studies

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Objective This systematic review aimed to assess the cost‐effectiveness of decompressive craniectomy (DC) in severe traumatic brain injury (TBI) patients by analyzing relevant economic studies. Methods The authors conducted a comprehensive search across multiple databases and included economic evaluation studies, clinical trials, observational
William Andrés Florez‐Perdomo   +11 more
wiley   +1 more source

Treadmill Training Improves Functional Recovery After Injection of Adipose‐Derived Stromal Vascular Fraction in Rats With a Spinal Cord Injury

open access: yesJournal of Neuroscience Research, Volume 104, Issue 9, September 2026.
In this study, we investigated the effect of a strategy combining stromal vascular fraction (SVF) autograft with treadmill training after a spinal cord injury in rats. SVF injection was performed within the 4 h post‐injury. Analysis was performed using behavior tests (BBB and ladder climbing tests), gait analysis on a walking corridor, and ...
Céline Ertlen   +7 more
wiley   +1 more source

Predictive factors of epidural blood patch success in intracranial hypotension syndrome

open access: yesHeadache: The Journal of Head and Face Pain, Volume 66, Issue 8, Page 1847-1858, September 2026.
Abstract Objective This study aimed to identify predictors of epidural blood patch (EBP) success in patients with intracranial hypotension syndrome. Background The epidural blood patch remains the gold standard treatment for intracranial hypotension syndrome, yet its effectiveness varies, and predictors of sustained success remain uncertain. Methods We
Anna Le Moal‐Baczynski   +13 more
wiley   +1 more source

Prognostic Factors for Postoperative Complications. An Aggregate Protocol for 10 Observational Studies From the Danish TRIPLE‐A Cohort of 1.2 Million Surgeries

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Postoperative complications substantially increase morbidity, mortality and healthcare costs. Understanding prognostic factors is essential for risk stratification, targeted prevention strategies, and development of prediction models.
Anders Peder Højer Karlsen   +15 more
wiley   +1 more source

Biomarker‐Based Diagnosis and Care Pathways for Alzheimer's Disease in the Era of Disease‐Modifying Treatments: A Consensus Statement by Belgian Experts

open access: yesEuropean Journal of Neurology, Volume 33, Issue 8, August 2026.
ABSTRACT Background The recent approval of disease‐modifying therapies (DMTs) for early Alzheimer's disease (AD) marks a major shift in clinical practice. Biomarker confirmation of amyloid pathology is now required alongside clinical assessment, and blood‐based tests are improving accessibility.
Tim Van Langenhove   +31 more
wiley   +1 more source

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