Results 91 to 100 of about 940,923 (283)

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source

The orientation of galaxy pairs with filamentary structures: dependence on morphology

, 2018
Aims. With the aim of performing an analysis of the orientations of galaxy pair systems with respect to the underlying large-scale structure, we study the alignment between the axis connecting the pair galaxies and the host cosmic filament where the pair
Alonso, Sol, Coldwell, Georgina, Duplancic, Fernanda, Jofré, M. Rosa Muñoz, Lambas, Diego G., Mesa, Valeria   +5 more
core   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Open versus minimally invasive TLIF: literature review and meta-analysis

Journal of Orthopaedic Surgery and Research, 2019
Study design This study is a comparative, literature review. Objective The aim of this study is to provide a comparative analysis of open vs. minimally invasive TLIF using a literature review and a meta-analysis.
Ahmed Hammad, André Wirries, Ardavan Ardeshiri, Olexandr Nikiforov, Florian Geiger   +4 more
doaj   +1 more source

TBK1‐Associated Primary Lateral Sclerosis Followed by Right Temporal Variant Frontotemporal Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We report a 58‐year‐old woman with a novel splice‐site variant in the TANK‐binding kinase 1 (TBK1:c.993–2A>C p.Ala332TyrfsTer39) who sequentially developed primary lateral sclerosis (PLS) followed by right temporal variant frontotemporal dementia (rtvFTD). Neuroimaging demonstrated right anterior temporal atrophy before cognitive symptoms, and
Tomoyasu Matsubara, Naoki Kihara, Satoko Miyatake, Koji Fujita, Konoka Tachibana, Ryosuke Miyamoto, Hiroki Yamazaki, Yusuke Osaki, Nazere Keyoumu, Yuki Kuwano, Nobutoshi Morimoto, Suzuran Saito, Eriko Koshimizu, Yoichi Otomi, Kenji Ishibashi, Masafumi Harada, Naomichi Matsumoto, Hiroyuki Morino, Yuishin Izumi   +18 more
wiley   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Comparison of pulmonary functions in double major idiopathic scolioisis patients operated using either hybrid or anterior vertebral body tethering techniques after minimum 2 years follow-up

Brain and Spine, 2021
Sinan Kahraman, Sanem Eryilmaz Polat, Sina Coskun, Recep Dincer, Mustafa Eltayep, Ahmet Ates, Ugur Tasci, Ayhan Mutlu, Tunay Sanli, Meric Enercan, Selhan Karadereler, Azmi Hamzaoglu   +11 more
doaj   +1 more source

Spine-sheath layer radiative interplay in subparsec-scale jets and the TeV emission from M87

, 2008
Simple one-zone homogeneous synchrotron self-Compton models have severe difficulties in explaining the TeV emission observed in the radiogalaxy M87.
Fabrizio Tavecchio, Gabriele Ghisellini, Harris D. E., Harris D. E., Marconi A., Stawarz L.   +5 more
core   +2 more sources

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane, Giorgia Coratti, Chiara Cutrì, Antonio Varone, Riccardo Masson, Adele D'Amico, Valeria Sansone, Sonia Messina, Federica Ricci, Chiara Ticci, Claudio Bruno, Caterina Agosto, Francesca Benedetti, Antonella Pini, Sabrina Siliquini, Massimiliano Filosto, Alberto Zambon, Ilaria Bitetti, Maria Rosaria Manna, Claudia Dosi, Riccardo Zanin, Stefano Parravicini, Roberto De Sanctis, Giulia Stanca, Michela Catteruccia, Michele Tosi, Irene Mizzoni, Emilio Albamonte, Valentina Franchino, Maria Sframeli, Ilaria Cavallina, Elena Procopio, Michele Sacchini, Simone Morando, Noemi Brolatti, Federica Trucco, Gaia Scarpini, Elena Briganti, Beatrice Berti, Concetta Palermo, Daniela Leone, Stefano C. Previtali, Eugenio Mercuri, the ITASMAC working group   +43 more
wiley   +1 more source

Clinical and radiologic outcomes and pulmonary functions after vertebral body tethering for immature adolescent idiopathic scoliosis: Minimum 2 years follow up

Brain and Spine, 2021
Mustafa Eltayep, Sinan Kahraman, Ahmet Ates, Recep Dincer, Sina Coskun, Ugur Tasci, Seray Gur, Ayhan Mutlu, Sanem Eryilmaz Polat, Tunay Sanli, Selhan Karadereler, Meric Enercan, Azmi Hamzaoglu   +12 more
doaj   +1 more source