Results 201 to 210 of about 55,555 (275)

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

open access: yesAdvanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji   +7 more
wiley   +1 more source

Evaluating Cytocompatibility of Corynebacterium glutamicum‐poly Vinyl Alcohol Living Biomaterials for Ocular Use

open access: yesAdvanced Healthcare Materials, EarlyView.
In ophthalmology, living biomaterials such as living contact lenses appear promising for sustained drug delivery or biosensing. The cytocompatibility of Cg‐PVA hydrogels, developed as a model living contact lens, is investigated with the ocular surface, showing their potential translation to the clinic.
Krupansh Desai   +6 more
wiley   +1 more source

Hybrid Nanofibers for Multimodal Accelerated Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
Fabrication of wound healing scaffolds based on biocompatible nanofibers. Nanofibers offering high surface area, flexibility, and biocompatibility significantly improved the healing outcome in vivo. Histological, immunological, and anti‐inflammatory markers are noticeably better in treated wounds.
Viraj P. Nirwan   +15 more
wiley   +1 more source

Giving It a Twist: One‐Step Fabrication of Aligned Biomimetic Yarn Scaffolds via Rotational Melt Electrofibrillation

open access: yesAdvanced Healthcare Materials, EarlyView.
Due to its multifunctionality, replicating the fibrillar and supramolecular architecture of Collagen I is gaining increasing priority in regenerative medicine. Using rotational Melt Electrofibrillation, we present a powerful method to accurately mimic the ultrastructure of Collagen with polycaprolactone, enabling the one‐step fabrication of three ...
Zan Lamberger   +11 more
wiley   +1 more source

Delivery of Multifunctional Microspheres via Intravesical Instillation for Bladder Carcinoma: Therapeutic Potential and Mechanistic Insights

open access: yesAdvanced Healthcare Materials, EarlyView.
PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu   +4 more
wiley   +1 more source

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