Results 51 to 60 of about 2,684 (177)
Ten Minutes Vestibular Examinations but Persistent Rehabilitative Exercises [PDF]
, 2013 Symposium on Neurology Highlight - S16Vertigo is a common illness that patients seek consultation in ENT clinics. Patients often have a hallucination of environmental rotation while patients with dizziness often have a sense of lightheadedness.
Au, DKK
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Spinocerebellar ataxias: genotype-phenotype correlations in 104 Brazilian families [PDF]
, 2012 OBJECTIVE: Spinocerebellar ataxias are neurodegenerative disorders involving the cerebellum and its connections. There are more than 30 distinct subtypes, 16 of which are associated with an identified gene.
Arruda, Walter O. +6 more
core +5 more sources
Advanced Science, Volume 13, Issue 11, 23 February 2026.This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva +28 more
wiley +1 more source
Progression of brain atrophy in spinocerebellar ataxia type 2: A longitudinal tensor-based morphometry study [PDF]
, 2014 Spinocerebellar ataxia type 2 (SCA2) is the second most frequent autosomal dominant inherited ataxia worldwide. We investigated the capability of magnetic resonance imaging (MRI) to track in vivo progression of brain atrophy in SCA2 by examining twice 10
Aiello, Marco +12 more
core +4 more sources
Functional changes of mentalizing network in SCA2 patients: novel insights into understanding the social cerebellum [PDF]
, 2020 In recent years, increasing evidence of the cerebellar role in social cognition has emerged. The cerebellum has been shown to modulate cortical activity of social brain regions serving as a regulator of function-specific mentalizing and mirroring ...
Bozzali, M +9 more
core +1 more source
Annals of Neurology, Volume 99, Issue 2, Page 502-522, February 2026.Objective An enduring puzzle in many inherited neurological disorders is the late onset of symptoms despite expression of function‐impairing mutant protein early in life. We examined the basis for onset of impairment in spinocerebellar ataxia type 6 (SCA6), a canonical late‐onset neurodegenerative ataxia which results from a polyglutamine expansion in ...
Haoran Huang +10 more
wiley +1 more source
Novel Missense Mitochondrial ND4L Gene Mutations in Friedreich's Ataxia [PDF]
, 2011 Objective(s)The mitochondrial defects in Friedreich's ataxia have been reported in many researches. Mitochondrial DNA is one of the candidates for defects in mitochondrion, and complex I is the first and one of the largest catalytic complexes of ...
Mehri Khatami, Mohammad Mehdi Heidari
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ON THE CLINICAL PICTURE OF CEREBELLAR ATROPHIES [PDF]
, 2017 No ...
Geneva, S. +3 more
core +2 more sources
Purkinje Cell Loss in Essential Tremor: Collective Data From 215 Brains Over a 21‐Year Period
Annals of Clinical and Translational Neurology, Volume 13, Issue 1, Page 36-48, January 2026.ABSTRACT Objective Essential tremor is a highly prevalent movement disorder. Pathological changes observed in essential tremor cerebella center around Purkinje cells and neighboring neuronal populations. Postmortem studies have variably, but not always, shown reduced Purkinje cell counts in essential tremor compared to controls.
Chloë A. Kerridge +4 more
wiley +1 more source
Neurodegeneration as a consequence of failed mitochondrial maintenance [PDF]
, 2018 Maintaining the functional integrity of mitochondria is pivotal for cellular survival. It appears that neuronal homeostasis depends on high-fidelity mitochondria, in particular.
Karbowski, Mariusz, Neutzner, Albert
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