Results 41 to 50 of about 811 (264)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Learning about Quantum Gravity with a Couple of Nodes

Symmetry, Integrability and Geometry: Methods and Applications, 2012
Loop Quantum Gravity provides a natural truncation of the infinite degrees of freedom of gravity, obtained by studying the theory on a given finite graph. We review this procedure and we present the construction of the canonical theory on a simple graph,
Enrique F. Borja, Iñaki Garay, Francesca Vidotto   +2 more
doaj   +1 more source

Spinors and conformal correlators

Journal of High Energy Physics, 2022
In conformal field theory, momentum eigenstates can be parameterized by a pair of real spinors, in terms of which special conformal transformations take a simpler form.
Marc Gillioz
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Spinors: A Mathematica package for doing spinor calculus in General Relativity [PDF]

Computer Physics Communications, 2012
12 pages, one figure. Typos corrected and references added.
Alfonso García-Parrado Gómez-Lobo, José M. Martín-García   +1 more
openaire   +6 more sources

Equivalence of regular spinor fields

European Physical Journal C: Particles and Fields
In the Lounesto classification, there are three types of regular spinors. They are classified by the condition that at least one of the scalar or pseudo scalar norms are non-vanishing. The Dirac spinors are regular spinors because their scalar and pseudo
Cheng-Yang Lee
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

On Poisson transforms for spinors

Tunisian Journal of Mathematics, 2023
Let $(τ,V_τ)$ be a spinor representation of $\mathrm{Spin}(n)$ and let $(σ,V_σ)$ be a spinor representation of $\mathrm{Spin}(n-1)$ that occurs in the restriction $τ_{\mid \mathrm{Spin}(n-1)}$. We consider the real hyperbolic space $H^n(\mathbb R)$ as the rank one homogeneous space $\mathrm{Spin}_0(1,n)/\mathrm{Spin}(n)$ and the spinor bundle $ΣH^n ...
Ben Saïd, Salem, Boussejra, Abdelhamid, Koufany, Khalid   +2 more
openaire   +2 more sources