Results 101 to 110 of about 233,450 (266)

Spiraled Origins [PDF]

Molecular Cell, 2005
Recent studies have established that the eukaryotic actin-based cytoskeleton has prokaryotic origins. In addition to regulating cell shape and polarity, Gitai et al. (2005) provide convincing evidence that the Caulobacter actin homolog MreB also mediates the early segregation of the chromosomal origin, a typical functional role of the eukaryotic ...
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Do bars drive spiral density waves? [PDF]

, 2009
We present deep near-infrared Ks-band Anglo-Australian Telescope Infrared Imager and Spectrograph observations of a selected sample of nearby barred spiral galaxies, including some with the strongest known bars.
IVANIO PUERARI
core  

Increased angiogenic factor secretion by decidual natural killer cells from pregnancies with high uterine artery resistance alters trophoblast function. [PDF]

, 2014
STUDY QUESTION Are the concentrations of factors secreted by decidual natural killer (dNK) cells from pregnancies at high risk of poor spiral artery remodelling different to those secreted from pregnancies at low risk?
Whitley, G S, Goulwara, S S, Johnstone, A P, Cartwright, JE, Whitley, GS, Goulwara, SS, Cartwright, J E, Wallace, A E, Fraser, R, Gurung, S, Wallace, AE, Johnstone, AP   +11 more
core   +1 more source

Design and Construction of a 500–800 MHz Square Spiral Dipole Microstrip Antenna Structure

Journal of Electrical Engineering and Computer
An antenna can be used to detect an object. The dimensions of the antenna also affect the working frequency, the smaller dimensions, the higher the working frequency and the closer the antenna range to radiate waves.
Arif Milando Setiawan
doaj   +1 more source

«Лабиринты» Молдажара

Искусство Евразии, 2018
В наскальном искусстве западной части хребта Тарбагатай (Восточный Казахстан) выявлены спиралевидные фигуры, которые, по-видимому, изображали лабиринты – такие фигуры достаточно распространены в петроглифах Евразии и обычно связываются с представлениями ...
Байтенов, Эскандер Муслимович
doaj   +1 more source

Spiral flames

Applied Mathematics Letters, 2003
This short paper is to describe computations of periodic and meandering spiral patterns in a reaction-diffusion model of flames, regarding the existence of spiral structures and their evolution as functions of the parameters which are representatives of combustion.
Alexander V. Panfilov, Alvin Bayliss, Bernard J. Matkowsky   +2 more
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source