Results 231 to 240 of about 12,684 (325)

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

open access: yesAdvanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai   +8 more
wiley   +1 more source

Spiral arms across stellar populations in hydrodynamical simulations

open access: yes
The majority of galaxies in the Local Universe are spiral galaxies. However, the formation and evolution of spiral arms is not well understood. Different theories explaining how spiral arms work give different predictions on their rotation and relative ...
Semczuk, M.   +3 more
core  

Structure and kinematics of the molecular spiral arms in M51

open access: yes, 1987
Mapping of the CO(1-0) emission from the spiral galaxy was made with the Onsala 20 m antenna. The observations show that the emission is considerably enhanced in spiral arms which appear to originate as intense ridges of emission about 1 kpc from the ...
Wiklind, T.   +4 more
core  

Tunable High‐Performance Metamaterial Filters Based on Novel SRR Architectures

open access: yesAdvanced Science, EarlyView.
Based on two novel SRR configurations and two independent SRR integration approaches, four tunable bandpass metamaterial filters were fabricated with an ultra‐thin ceramic substrate. Among them, SM‐2 achieves over 97% electromagnetic wave transmittance, with a minimal 1.15% deviation in its resonant frequency prediction, making them promising ...
Lingxi Qu   +4 more
wiley   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

open access: yesAdvanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li   +8 more
wiley   +1 more source

A misaligned protostellar disk fed by gas streamers in a barred spiral-like massive dense core. [PDF]

open access: yesSci Adv
Mai X   +44 more
europepmc   +1 more source

An Energy Autonomous Microneedle Array‐Based Sensing System for Continuous Biomarker Monitoring

open access: yesAdvanced Science, EarlyView.
This work presents an innovative self‐powered wearable biosensor system for real‐time monitoring of multiple biomarkers in interstitial fluid. The device integrates stainless steel‐based minimally invasive microneedles with ion‐selective membranes, enabling simultaneous Na+, K+, Ca2+, pH, and glucose detection.
Arnab Pal   +9 more
wiley   +1 more source

Intention Tremor Severity Trajectory: Results from a Prospective Longitudinal Study of Essential Tremor. [PDF]

open access: yesTremor Other Hyperkinet Mov (N Y)
Louis ED   +5 more
europepmc   +1 more source

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