Decidual Vasculopathy in Preeclampsia and Spiral Artery Remodeling Revisited: Shallow Invasion versus Failure of Involution [PDF]
Decidual vasculopathy is commonly associated with preeclampsia and develops in the late pregnancy in the uterine spiral arteries, which were previously remodeled by the extravillous trophoblasts.
Peilin Zhang
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Spiral Vein Graft Reconstruction for an Infected Common Femoral Artery Pseudoaneurysm after Vascular Closure Device and Stent-Graft Failure: A Case Report [PDF]
Vascular closure devices (VCDs) allow rapid hemostasis after endovascular procedures but may rarely cause pseudoaneurysms or infections. Infected pseudoaneurysms of the common femoral artery (CFA) following VCD use are uncommon, and stent-graft exclusion
Eol Choi
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Fluorescence imaging of arterial blood spiral laminar flow of rats [PDF]
Objective To estatblish a real-time fluorescence imaging method for observing arterial blood spiral laminar flow. Methods Sprague Dawley rats were randomly divided into vein angiography group (femoral vein injection, 1 mL/kg) and low-dose arteriography ...
QI Xi, LI Bei, LI Hongyi, LI Yansong, ZHAO Lihao, HAO You, YU Xue
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Introduction: Hyperglycemic conditions achieved during pregnancy have been shown to have detrimental effects to fetal development and increase the prevalence of childhood comorbidities.
Yushu Qin +6 more
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Pathogenesis of Preeclampsia and Therapeutic Approaches Targeting the Placenta
Preeclampsia (PE) is a serious pregnancy complication, affecting about 5–7% of pregnancies worldwide and is characterized by hypertension and damage to multiple maternal organs, primarily the liver and kidneys. PE usually begins after 20 weeks’ gestation
Manoj Kumar Jena +4 more
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Spiral Artery Remodeling in Preeclampsia Revisited [PDF]
See related article, pp 1046–1054 The first observations that placental bed defects were potentially linked to clinical outcomes such as preeclampsia (PE) were made nearly 50 years ago.1 This study followed prior findings that the placental clearance of radiolabeled saline was significantly decreased in women with hypertensive gestations.2 ...
Suzanne D, Burke, S Ananth, Karumanchi
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Human Spiral Artery Renin-Angiotensin System [PDF]
Abstract —Pregnancy induces uterine spiral arteries to remodel into dilated uteroplacental vessels by an unknown mechanism called “physiological change.” In women who develop preeclampsia, however, many spiral arteries remain unchanged or develop medial hyperplasia and atherosis. We recently demonstrated that angiotensinogen is
T, Morgan, C, Craven, K, Ward
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Leukemia Inhibitory Factor (LIF) Inhibition during Mid-Gestation Impairs Trophoblast Invasion and Spiral Artery Remodelling during Pregnancy in Mice. [PDF]
The placenta forms the interface between the maternal and fetal circulation and is critical for the establishment of a healthy pregnancy. Trophoblast cell proliferation, migration and invasion into the endometrium are fundamental events in the initiation
Amy Winship +4 more
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Fetal-derived trophoblast use the apoptotic cytokine tumor necrosis factor-alpha-related apoptosis-inducing ligand to induce smooth muscle cell death. [PDF]
Remodeling of the uterine spiral arteries during pregnancy transforms them from high to low resistance vessels that lack vasoconstrictive properties. This process is essential to meet the demand for increased blood flow imposed by the growing fetus. Loss
Aplin, JD +6 more
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Induced Human Decidual NK-Like Cells Improve Utero-Placental Perfusion in Mice. [PDF]
Decidual NK (dNK) cells, a distinct type of NK cell, are thought to regulate uterine spiral artery remodeling, a process that allows for increased blood delivery to the fetal-placental unit.
Ricardo C Cavalli +10 more
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