Results 241 to 250 of about 45,533 (303)

Next Generation 7 Tesla Arterial Spin Labeling With Rotated Spiral Acquisition Enables Mesoscale Resolution in 3D Brain Perfusion and Functional MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To achieve high resolution (≤ 1 mm isotropic) whole‐brain perfusion imaging at 7 T with next generation ASL pulse sequence, reconstruction algorithm, and MRI hardware. Methods We capitalized on three major innovations: (1) FLASH‐based pseudo‐Continuous ASL (pCASL) sequence with rotated golden‐angle stack‐of‐spirals (rGA‐SoS) sampling; (
Chenyang Zhao, Fanhua Guo, Zidong Yang, Xingfeng Shao, Samantha J. Ma, Alexander J. S. Beckett, An T. Vu, David A. Feinberg, Danny J. J. Wang   +8 more
wiley   +1 more source

Effects and Correction of Patient Bulk Motion in Cranial DENSE MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Applications of DENSE to measure cardiac driven brain tissue pulsations are highly sensitive to bulk patient motion due to the sub‐millimeter displacement encoding required, limiting its accuracy, reproducibility, and use in pediatric and aging populations.
Caroline A. Doctor, Leonardo A. Rivera‐Rivera, Laura B. Eisenmenger, Sterling C. Johnson, Kevin M. Johnson   +4 more
wiley   +1 more source

Impaired implantation as a major upstream pathway of preeclampsia: a narrative synthesis of mechanistic, epidemiological and biomarker evidence. [PDF]

Front Reprod Health
Ibrahim A, Engku Ismail EH, Irwan Khoo M, Yusuf L, Nik Hussain NH, Mat Zin AA, Noordin L, Abdullah S, Mahdy ZA, Nik Lah NAZ.   +9 more
europepmc   +1 more source

Dynamic Contrast Enhanced—Magnetic Resonance Fingerprinting (DCE‐MRF) Improves Detection of Induced Vascular Perfusion Reduction in a Mouse Breast Cancer Model

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Dynamic contrast‐enhanced MRI (DCE‐MRI) can assess tumor perfusion using pharmacokinetic models. However, poor DCE‐MRI reproducibility from reliance on conventional T1‐weighted MRI has limited clinical translation. We evaluated whether Dynamic Contrast Enhanced‐Magnetic Resonance Fingerprinting (DCE‐MRF), which directly generates ...
Christina J. MacAskill, Bernadette O. Erokwu, Yuran Zhu, Guanhua Wang, Andrew Dupuis, Barbara J. Schiemann, Gopalakrishnan Ramamurthy, Chetan B. Dhakan, Michael Kavran, Chunying Wu, William P. Schiemann, Yilun Sun, Mark A. Griswold, Xin Yu, Mark D. Pagel, Chris A. Flask   +15 more
wiley   +1 more source

Reuniting and Endolymphatic Duct Macrophages: Localization and Possible Roles. [PDF]

Audiol Res
Vivado E, Cossellu D, Perin P.
europepmc   +1 more source

Toward Optimized Intravoxel Incoherent Motion (IVIM) and Compartmental T2 Mapping in Abdominal Organs

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To quantitatively assess the bias in the intravoxel incoherent motions (IVIM)–derived pseudo‐diffusion volume fraction (f) caused by the differences in relaxation times between the tissue and fluid compartments, and to develop a two‐dimensional (b‐value‐TE) fitting approach for simultaneous T2 and IVIM parameter estimation along with ...
Julia Stabinska, Thomas A. Thiel, Hans‐Jörg Wittsack, Alexandra Ljimani, Helge J. Zöllner   +4 more
wiley   +1 more source

Computational Evaluation of Statin Analogs Targeting HMG‐CoA Reductase for Coronary Artery Disease Treatment

ChemistryOpen, EarlyView.
Molecular dynamics analysis of novel statin analogs shows that binding induces superior stabilization of HMG‐CoA reductase. As shown by the solvent‐accessible surface area profile, ligand‐induced rigidity offers a new, effective strategy for drug design. Cardiovascular diseases remain a leading cause of global mortality.
Yoshua B. Mtulo, Geradius Deogratias, James E. Mgaya, Andrew S. Paluch, Lucas Paul   +4 more
wiley   +1 more source

Maternal causation of early-onset pre-eclampsia: excessive endometrial gland-derived apolipoprotein D induces placental ferroptosis and developmental abnormalities. [PDF]

J Biomed Sci
Dong Y, Lee CL, Li J, Liu X, Zeng Q, Zhong J, Zhang Q, Wu T, Ng VWY, Lee CKF, Burton GJ, Ng EHY, Yeung WSB, Cheung KW, Chiu PCN.   +14 more
europepmc   +1 more source

The Prediction of Pre‐Eclampsia Using Low Fetal Fraction in a Machine Learning Model

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To investigate the association between low fetal fraction (FF) in non‐invasive prenatal testing (NIPT) and pregnancy complications or adverse pregnancy outcomes. Methods Sixty‐four pregnant women undergoing NIPT at the Second Affiliated Hospital of Wenzhou Medical University between 13 June 2019 and 6 January 2023 had an initial NIPT
Jinyuan Wang, Yuxiao Bai, Shengshan Huang, Yao Lin, Songdao Ye, Wangxiao Zhou, Shanshan Li, Ni Li, Minghua Jiang, Xiaoou Wang   +9 more
wiley   +1 more source

Surgical treatment of postinfarction thrombosed left ventricle aneurysm formed from coronary artery dissection. [PDF]

Am Heart J Plus
Gogayeva OK, Nudchenko OO, Rudenko ML, Rudenko AV.   +3 more
europepmc   +1 more source