Uterine spiral artery muscle dedifferentiation
AbstractSTUDY QUESTIONIs vascular smooth muscle cell (VSMC) dedifferentiation a feature of uterine spiral artery (SpA) remodelling in early human pregnancy?SUMMARY ANSWERRemodelling of human uterine SpAs is associated with dedifferentiation of VSMCs and can be induced in vitro by uterine natural killer (uNK) cells and extravillous trophoblast cells ...
A, Robson +5 more
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Investigation of spiral blood flow in a model of arterial stenosis [PDF]
The spiral component of blood flow has both beneficial and detrimental effects in human circulatory system [Stonebridge PA, Brophy CM. Spiral laminar flow in arteries? Lancet 1991; 338: 1360–1].
Ahmed +16 more
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Reduction of radiation dose for coronary computed tomography angiography using prospective electrocardiography-triggered high-pitch acquisition in clinical routine [PDF]
Purpose: To evaluate the image quality, radiation exposure, and means of application in a group of patients who underwent coronary computed tomography angiography (CCTA) performed with low-dose prospective electrocardiography (ECG)-triggered acquisition ...
Chaosuwannakit, Narumol +1 more
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Gender differences in myogenic regulation along the vascular tree of the gerbil cochlea. [PDF]
Regulation of cochlear blood flow is critical for hearing due to its exquisite sensitivity to ischemia and oxidative stress. Many forms of hearing loss such as sensorineural hearing loss and presbyacusis may involve or be aggravated by blood flow ...
Katrin Reimann +3 more
doaj +1 more source
Uterine spiral artery remodeling involves endothelial apoptosis induced by extravillous trophoblasts through Fas/FasL interactions. [PDF]
Objective— Invasion of uterine spiral arteries by extravillous trophoblasts in the first trimester of pregnancy results in loss of endothelial and musculoelastic layers.
Ashton, SV +6 more
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Successful Bail-Out Stenting for Iatrogenic Right Coronary Artery Dissection in a Young Male
Catheter-induced coronary artery dissection is a serious complication of coronary angiography. Percutaneous intervention is usually indicated in case of large spiral dissections, however, wiring into the true lumen can be challenging.
Shahrukh Hashmani, MBBS +2 more
doaj +1 more source
Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy. [PDF]
Rats harboring the human angiotensinogen and human renin genes develop preeclamptic features in pregnancy. The preeclamptic rats exhibit a deeper trophoblast invasion associated with a reduced resistance index by uterine Doppler.
Cartwright, JE +12 more
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Interleaved spiral cine coronary artery velocity mapping [PDF]
Navigator-echo controlled interleaved spiral cine coronary-artery velocity maps were acquired in eight free-breathing volunteers. Good quality data were achieved in all subjects with phasic flow being clearly demonstrated. The improved efficiency of spiral k-space coverage compared to that of more conventional spin-warp techniques resulted in a mean ...
J, Keegan +3 more
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Accumulating evidence has shown that preeclampsia (PE) was associated with an aberrant maternal-fetal inflammatory response. In the present study, we first found that in human PE placentas levels of toll-like receptor 4 (TLR4), phosphorylated p38 mitogen-
Minghua Fan +7 more
doaj +1 more source
Impaired decidual natural killer cell regulation of vascular remodelling in early human pregnancies with high uterine artery resistance [PDF]
During human pregnancy, natural killer (NK) cells accumulate in the maternal decidua, but their specific roles remain to be determined. Decidual NK (dNK) cells are present during trophoblast invasion and uterine spiral artery remodelling.
Cartwright, JE +6 more
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