Impaired decidual natural killer cell regulation of vascular remodelling in early human pregnancies with high uterine artery resistance [PDF]
During human pregnancy, natural killer (NK) cells accumulate in the maternal decidua, but their specific roles remain to be determined. Decidual NK (dNK) cells are present during trophoblast invasion and uterine spiral artery remodelling.
Cartwright, JE+6 more
core +1 more source
Gender differences in myogenic regulation along the vascular tree of the gerbil cochlea. [PDF]
Regulation of cochlear blood flow is critical for hearing due to its exquisite sensitivity to ischemia and oxidative stress. Many forms of hearing loss such as sensorineural hearing loss and presbyacusis may involve or be aggravated by blood flow ...
Katrin Reimann+3 more
doaj +1 more source
Failure of physiologic transformation of spiral arteries, endothelial and trophoblast cell activation, and acute atherosis in the basal plate of the placenta [PDF]
BACKGROUND: Failure of physiologic transformation of spiral arteries has been reported in preeclampsia, fetal growth restriction, fetal death, and spontaneous preterm labor with intact or ruptured membranes. Spiral arteries with failure of physiologic
Bammerlin, Elaine+8 more
core +1 more source
Inhibition of Trophoblast-Induced Spiral Artery Remodeling Reduces Placental Perfusion in Rat Pregnancy. [PDF]
Rats harboring the human angiotensinogen and human renin genes develop preeclamptic features in pregnancy. The preeclamptic rats exhibit a deeper trophoblast invasion associated with a reduced resistance index by uterine Doppler.
Cartwright, JE+12 more
core +1 more source
Accumulating evidence has shown that preeclampsia (PE) was associated with an aberrant maternal-fetal inflammatory response. In the present study, we first found that in human PE placentas levels of toll-like receptor 4 (TLR4), phosphorylated p38 mitogen-
Minghua Fan+7 more
doaj +1 more source
Uterine spiral artery remodeling involves endothelial apoptosis induced by extravillous trophoblasts through Fas/FasL interactions. [PDF]
Objective— Invasion of uterine spiral arteries by extravillous trophoblasts in the first trimester of pregnancy results in loss of endothelial and musculoelastic layers.
Ashton, SV+6 more
core +1 more source
This article explores the CT findings and outcome of a case involving median arcuate ligament compression syndrome complicated with spontaneous isolated superior mesenteric artery dissection.
Xue HAN+3 more
doaj +1 more source
Effects of Circulating and Local Uteroplacental Angiotensin II in Rat Pregnancy. [PDF]
The renin-angiotensin (Ang) system is important during placental development. Dysregulation of the renin-Ang system is important in preeclampsia (PE). Female rats transgenic for the human angiotensinogen gene crossed with males transgenic for the human ...
Brosnihan, KB+12 more
core +1 more source
Human Spiral Artery Renin-Angiotensin System [PDF]
Abstract —Pregnancy induces uterine spiral arteries to remodel into dilated uteroplacental vessels by an unknown mechanism called “physiological change.” In women who develop preeclampsia, however, many spiral arteries remain unchanged or develop medial hyperplasia and atherosis. We recently demonstrated that angiotensinogen is
Kenneth Ward+2 more
openaire +3 more sources
Color Doppler analysis of female reproductive vasculature in Behçet’s disease
Behçet’s disease (BD) may affect female reproductive vasculature. We aimed to evaluate Doppler sonographic characteristics of female reproductive vasculature and also ovarian volume, endometrial thickness (EMT) and antral follicle count of BD patients in
M.E. Tezcan+6 more
doaj +1 more source