Results 21 to 30 of about 30,660 (267)

Radiologic Diagnosis of Gastrointestinal Bleeding

open access: yesJournal of the Korean Society of Radiology, 2023
Gastrointestinal (GI) bleeding is not a single disease but a symptom and clinical manifestation of a broad spectrum of conditions in the GI tract. According to its clinical presentation, GI bleeding can be classified into overt, occult, and obscure ...
Se Hyung Kim
doaj   +1 more source

Anastomosing Hemangioma Involving the Para-Aortic Region: A Case Report

open access: yes대한영상의학회지, 2017
Anastomosing hemangioma (AH) is a rare and benign vascular neoplasm that is regarded as a morphological variant of capillary hemangioma. AH has been encountered primarily in the kidney.
Jung Min Lee   +4 more
doaj   +1 more source

Differential diagnosis of prosopalgia of dental patients

open access: yesЭндодонтия Today, 2023
Aim. To estimate the size of the areas of the skull holes along the course of the trigeminal nerve in dental patients with prosopalgia according to computed tomography. Materials and methods. Twenty seven dental patients were examined.
R. A. Mikhailik   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

New Imaging Techniques in the Evaluation of Gastrointestinal Diseases

open access: yesCanadian Journal of Gastroenterology, 2000
This article provides an overview of recently developed, noninvasive imaging modalities for the evaluation of gastrointestinal disease processes. The advent of spiral computed tomography, magnetic resonance cholangiopancreatography and conventional ...
Faranak Tafazoli   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Evaluation of the absorbed dose of the thyroid gland in conventional spiral and spiral computed tomography techniques

open access: yesمجله دانشکده دندانپزشکی اصفهان, 2012
Introduction: The use of sophisticated radiographic techniques is absolutely necessary in dentistry. The use of these techniques exposes the sensitive organs of head and neck to x-rays. The aim of the present study was to investigate the absorbed dose of
Hamid Badrian   +3 more
doaj  

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