Results 21 to 30 of about 12,116,218 (244)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Educational Needs Assessment of Spiritual Care in Nurses in Iran in 2021: Using Delphi Technique

open access: yesHealth, Spirituality and Medical Ethics, 2021
Background and Objectives: Nurses are professionally and ethically obliged to provide spiritual care as part of comprehensive care for patients. The present study was conducted to determine the educational needs of nurses to provide spiritual care ...
Ashraf KHoramirad   +6 more
doaj  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

The relationship between denominational affiliation and spiritual health among weekly-churchgoing 13- to 15-year-old adolescents in England and Wales [PDF]

open access: yes, 2008
THIS PAPER DRAWS on John Fisher’s formative definition of spiritual health as comprising good relationships within four domains (the personal, the communal, the environmental and the transcendental) and uses the operationalization of these constructs ...
Robbins, Mandy, Francis, Leslie J.
core  

Structural validity of a brief scale adapted to measure adolescent spiritual health. [PDF]

open access: yes, 2021
Spiritual health is established as an important protective health asset in child populations. Measurement and assessment of this elusive concept are, however, challenging.
Whitehead, R   +6 more
core   +1 more source

How to develop strategic and operational plan for research institute; a qualitative approach

open access: yesSocial Determinants of Health, 2021
Background: Spiritual health is recognized as one of the dimensions of health in Iran and in recent years many studies are conducted in this field in the country. This study aimed to review the experience of developing a five-year strategic plan and a
Sahand Riazi-Isfahani   +4 more
doaj   +1 more source

Understanding the Burden of Orofacial Involvement and Patient Treatment Preferences in Systemic Sclerosis: Results From a Large International Survey

open access: yesArthritis Care &Research, EarlyView.
Objective Orofacial manifestations are significantly impactful in patients with systemic sclerosis (SSc) yet remain understudied, with no dedicated clinical guidelines to inform their management. Methods An international online survey comprised38 questions addressing orofacial manifestations of SSc, including patients’ confidence in their treating ...
Eleni Deligianni   +4 more
wiley   +1 more source

Volunteer Caregivers’ Empowerment for the Care of COVID-19 Patients: An Experience in Iran

open access: yesBasic and Clinical Neuroscience, 2020
This article has no abstract.
Akram Heidari   +4 more
doaj  

Clinician and Patient Factors Associated With Long‐Term Glucocorticoid Use in People With Rheumatoid Arthritis Receiving Advanced Therapies

open access: yesArthritis Care &Research, EarlyView.
Objective Despite guideline recommendations, long‐term glucocorticoid (GC) use is common in rheumatoid arthritis (RA). We conducted a clinician survey nested within a large registry to identify patient and clinician factors associated with GC use. Methods Clinicians contributing patients to the CorEvitas Rheumatoid Arthritis Registry were surveyed ...
Michael D. George   +7 more
wiley   +1 more source

Effects of spiritual care training for palliative care professionals [PDF]

open access: yes, 2005
Little is known about the effects of spiritual care training for professionals in palliative medicine. We therefore investigated prospectively the effects of such training over a six-month period.
Borasio, Gian Domenico   +8 more
core   +1 more source

Home - About - Disclaimer - Privacy