Results 61 to 70 of about 12,116,218 (244)

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

Advanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang, Jinghan Zhu, Qian Xiao, Qichun Wei, Xiujing He, Ping Li, Kai Jiang, Yue Liu, Yeting Hu, Weiwei Yu, Chuansheng Guo, Sheng Chen, Jian Zhao, Siqi Dai, Jingsun Wei, Hang Yang, Tongtong Bu, Kefeng Ding, Haiyan Chen   +18 more
wiley   +1 more source

How clients with religious or spiritual beliefs experience psychological help-seeking and therapy: a qualitative study [PDF]

, 2007
This qualitative study explores the process of help-seeking and therapy among clients with religious or spiritual beliefs. Ten clients who were currently in, or had recently finished, therapy were interviewed.
Claire Mayers, Barker, C., Vallianatou, C., Leavey, G., Chris Barker, Mayers, C., Christina Vallianatou, Gerard Leavey   +7 more
core   +1 more source

Sense of coherence as a protective factor of health related quality of life in Iranian older adults

Discover Social Science and Health
Sense of coherence supports human well-being by using internal and external resources to cope with stress and maintain health. The study was conducted in Qom, Iran from June to October 2022 explored the relationship between sense of coherence and quality
Tahereh Komeili, Iman Khahan-Yazdi, Mohadeseh Sadri, Mahmoud Shokouhi-Tabar, Morteza Heidari, Zahra Taheri-Kharameh   +5 more
doaj   +1 more source

Student’s characteristics and fast food consumption

Chronic Diseases Journal, 2019
BACKGROUND: Fast food consumption is one of the risk factors for human health. The present study was conducted with the objective to investigate how students’ characteristics (attitude, control beliefs, and normative beliefs) motivate the consumption of ...
Shahram Sadeghi
doaj   +1 more source

KLF5 Downregulation Links Impaired BNIP3‐Mediated Mitophagy to Inflammatory Valve Remodeling in Calcific Aortic Valve Disease

Advanced Science, EarlyView.
In human CAVD, KLF5 is reduced in VIC‐rich regions and remodeling/stress‐associated VIC states. In VICs, KLF5 sustains BNIP3 promoter activity and BNIP3‐mediated mitophagy, thereby limiting cytosolic mtDNA accumulation. KLF5 loss weakens mitochondrial quality control and enhances mtDNA‐sensitive STING/NF‐κB/NLRP3 inflammatory signaling under osteogenic
Jin‐Hui Bian, Jia‐Xi Gu, Zhang Yue, Chun‐Ze Yuan, Hai‐Bin Ji, Ao Li, Yu Zhong, Xiu‐Fan Xu, Yu‐Qiu He, Ye‐Fan Jiang, Hong‐Shan Chen, Xiang Chen, Meng‐Lin Chao, Yong‐Feng Shao   +13 more
wiley   +1 more source

Relationship of Religious Attitude and Self-control with Quality of Life among the Students of University of Qom and Qom University of Medical Sciences: A Path Analysis

Health, Spirituality and Medical Ethics, 2019
Background and Objectives: Quality of life is a key component of health, associated with the individual and social living conditions of a person. Religious or spiritual parameters are among the most important determinants of quality of life (QOL) and its
Susan Bahrami, Morteza Heidari, Amir Hamta, Fatemeh Samadi, Akram Heidari   +4 more
doaj  

Caring for the caregivers: a scoping review of spiritual and religious interventions for family caregivers in home care

BMC Nursing
Background Family caregivers often experience stress, which negatively affects their well-being, health, and quality of life. This review of current studies on spiritual and religious interventions and their effects will contribute to the development of ...
Jenny Kubitza, Benedikt Kaiser, Ruth Mächler, Dagmar Teutsch, Juliane Stingl, Annette Haußmann, Eckhard Frick   +6 more
doaj   +1 more source

Decoding Viral Transmission Dynamics in Structured Populations Using a Microfluidic Herd‐Immunity‐on‐a‐Chip Platform

Advanced Science, EarlyView.
A microfluidic Herd‐Immunity‐on‐a‐Chip experimentally recreates structured contact networks to quantify viral transmission dynamics. By controlling susceptible, infected, and non‐susceptible populations, the platform reveals how contact topology governs the reproduction number, outbreak propagation, herd‐immunity–like behavior, and intervention ...
Jiande Zhang, Narina Jung, Min‐Hyeok Kim, Wanyoung Lim, Zhenzhong Chen, Byung Mook Weon, Sungsu Park   +6 more
wiley   +1 more source

Structural Basis of Lymphangiogenic Receptor VEGFR‐3 Activation Mediated by Distinctive Clustering of the Ligand–Receptor Complex

Advanced Science, EarlyView.
VEGF‐C and its receptor VEGFR‐3 are critical for lymphangiogenesis. Cryo‐EM structures of the VEGFR‐3/VEGF‐C ectodomain complex reveal a canonical 2:2 ligand–receptor hetero‐tetramer that further assembles into higher‐order clusters beyond simple receptor dimerization.
Ryeongeun Cho, Jinsook Ahn, Jimin Yang, Dong Sun Lee, Gahi Hong, Sangkyu Lee, Ho Min Kim   +6 more
wiley   +1 more source

Measuring spiritual belief: development and standardization of a Beliefs and Values Scale. [PDF]

, 2005
BACKGROUND: Higher levels of religious involvement are modestly associated with better health, after taking account of other influences, such as age, sex and social support.
Barnes, Kelly, Jones, L, Sutherland, J, Tookman, A, Adrian Tookman, Kelly Barnes, Joseph Low, Christina Mason, Carl Walker, Barnes, K, Juliette Sutherland, Susie Wilkinson, Sutherland, Juliette, King, M, Low, J, Louise Jones, Mason, Christina, Tookman, Adrian, Walker, Carl, Mason, C, Wilkinson, S, Jones, Louise, Wilkinson, Susie, Walker, C, King, Michael, Low, Joseph, Michael King   +26 more
core   +1 more source