Results 91 to 100 of about 5,314 (210)

The performance of modularity maximization in practical contexts

open access: yes, 2010
Although widely used in practice, the behavior and accuracy of the popular module identification technique called modularity maximization is not well understood in practical contexts.
Clauset, Aaron   +2 more
core   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Neutrophil Extracellular Traps (NETs) in the Cerebrospinal Fluid Samples from Children and Adults with Central Nervous System Infections

open access: yesCells, 2019
Neutrophils operate as part of the innate defence in the skin and may eliminate the Borrelia spirochaete via phagocytosis, oxidative bursts, and hydrolytic enzymes. However, their importance in Lyme neuroborreliosis (LNB) is unclear.
Daniel Appelgren   +10 more
doaj   +1 more source

Exploring the Key Role of Nanotechnology on Intratumoral Microbiome Modulation for Cancer Immunotherapy

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.
The review provides a comprehensive analysis of microbiome‐mediated oncogenic mechanisms in various cancers, emphasizing the unique therapeutic strategies facilitated by nanotechnology. It aims to fill this gap by systematically reviewing nanotechnology‐driven strategies for microbiome elimination, with a focus on their ability to improve the cold TME ...
Yumei Gan, Yan Zhang, Xia Dong, Feng Lv
wiley   +1 more source

A motif-based search in bacterial genomes identifies the ortholog of the small RNA Yfr1 in all lineages of cyanobacteria

open access: yesBMC Genomics, 2007
Background Non-coding RNAs (ncRNA) are regulators of gene expression in all domains of life. They control growth and differentiation, virulence, motility and various stress responses.
Axmann Ilka M   +3 more
doaj   +1 more source

Crosstalk Between Intratumoral Microbes and Tumor Immunity: Implications for Tumor Therapy

open access: yesCancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Emerging studies indicate that microbes are present in tumor cells and immune cells. Intratumoral microbiota (ITM) constitute an important component of the tumor immune microenvironment (TIME) and have an important impact on tumor progression and treatment. Objective Through the general elaboration of ITM represented by bacteria and
Fengxue Li   +13 more
wiley   +1 more source

Transcriptomics in the tropics: Total RNA-based profiling of Costa Rican bromeliad-associated communities

open access: yesComputational and Structural Biotechnology Journal, 2015
RNA-Seq was used to examine the microbial, eukaryotic, and viral communities in water catchments (‘tanks’) formed by tropical bromeliads from Costa Rica.
Shana K. Goffredi   +2 more
doaj   +1 more source

Multilocus sequence analysis of phylogroup 1 and 2 oral treponeme strains [PDF]

open access: yes, 2017
More than 75 ‘species-level' phylotypes of spirochete bacteria belonging to the genus Treponema reside within the human oral cavity. The majority of these oral treponeme phylotypes correspond to as-yet uncultivated taxa, or strains of uncertain standing ...
Chan, YK   +6 more
core   +1 more source

VapC from the leptospiral VapBC toxin-antitoxin module displays ribonuclease activity on the initiator tRNA.

open access: yesPLoS ONE, 2014
The prokaryotic ubiquitous Toxin-Antitoxin (TA) operons encode a stable toxin and an unstable antitoxin. The most accepted hypothesis of the physiological function of the TA system is the reversible cessation of cellular growth under stress conditions ...
Alexandre P Y Lopes   +8 more
doaj   +1 more source

Coevolution and Functional Effects of Endosymbiotic Rickettsia in Leptocybe invasa Fisher & LaSalle (Hymenoptera: Eulophidae) Across China

open access: yesEcology and Evolution, Volume 16, Issue 2, February 2026.
Two distinct lineages of L. invasa and the dominant endosymbiont, Rickettsia, was identified, followed by an analysis of its infection density across various developmental stages and tissues of L. invasa. Furthermore, two distinct strains of the Rickettsia endosymbiont were detected, and the phylogenetic relationships between these strains and their L.
Xiu Xu   +5 more
wiley   +1 more source

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